Evidence map›Paper›PMID 32279413›Full record

ArticleLiver international : official journal of the International Association for the Study of the Liver2020

A multicentre retrospective analysis on growth of residual hepatocellular adenoma after resection.

Anne J Klompenhouwer, Belle V van Rosmalen, Martijn P D Haring, Maarten G J Thomeer, Michail Doukas, Joanne Verheij, Vincent E de Meijer, Thomas M van Gulik, Robert B Takkenberg, Geert Kazemier and 3 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Liver international : official journal of the International Association for the Study of the Liver, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. A multicentre retrospective analysis on growth of residual hepatocellular adenoma after resection.Liver international : official journal of the International Association for the Study of the Liver · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Anne J KlompenhouwerDepartment of Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-6740-3862
Belle V van RosmalenDepartment of Surgery, Amsterdam University Medical Centers, University of Amsterdam (Location Academic Medical Center), Amsterdam, The Netherlands.
Martijn P D HaringDivision of Hepatopancreatobiliary Surgery and Liver Transplantation, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0003-4789-3910
Maarten G J ThomeerDepartment of Radiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Michail DoukasDepartment of Pathology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Joanne VerheijDepartment of Pathology, Amsterdam University Medical Centers, University of Amsterdam (Location Academic Medical Center), Amsterdam, The Netherlands.
Vincent E de MeijerDivision of Hepatopancreatobiliary Surgery and Liver Transplantation, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Thomas M van GulikDepartment of Surgery, Amsterdam University Medical Centers, University of Amsterdam (Location Academic Medical Center), Amsterdam, The Netherlands.
Robert B TakkenbergDepartment of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam (Location Academic Medical Center), Amsterdam, The Netherlands.
Geert KazemierDepartment of Surgery, Amsterdam University Medical Centers, University of Amsterdam (Location VU Medical Center), Amsterdam, The Netherlands.
Frederik NevensDepartment of Gastroenterology and Hepatology, University Hospital KU Leuven, Leuven, Belgium.
Robert A de ManDepartmnt of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Jan N M IjzermansDepartment of Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0003-3558-1039
Erasmus MC · NLAmsterdam UMC Location University of Amsterdam · NLUniversity Medical Center Groningen · NLAmsterdam University Medical Centers · NLKU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND &

aimsHepatocellular adenoma (HCA) is a benign liver tumour that may require resection in select cases. The aim of this study was to the assess growth of residual HCA in the remnant liver and to advise on an evidence-based management strategy.

methodThis multicentre retrospective cohort study included all patients with HCA who underwent surgery of HCA and had residual HCA in the remnant liver. Growth was defined as an increase of >20% in transverse diameter (RECIST criteria). Data on patient and HCA characteristics, diagnostic work-up, treatment and follow-up were documented and analysed.

resultsA total of 134 patients were included, one male. At diagnosis, median age was 38yrs (IQR 30.0-44.0) and median BMI was 29.9 kg/m

conclusionIn patients with multiple HCA who undergo resection, growth of residual HCA is not uncommon but interventions are rarely needed as most lesions stabilize and do not show progressive growth. Surveillance is indicated when residual HCA show growth after resection, enabling intervention in case of progressive growth.

Indexed as

Adenoma, Liver CellCarcinoma, HepatocellularLiver NeoplasmsAdultFemaleHumansMaleRetrospective Studiesadenoma liver cellfollow-up studiessurgical procedure

Identifiers

PMID32279413
PMCPMC7497037
OpenAlexW3015757819

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.