ArticleClinical and experimental immunology2020
The effects of advanced maternal age on T-cell subsets at the maternal-fetal interface prior to term labor and in the offspring: a mouse study.
Article in Clinical and experimental immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Physiological and Behavioural Characterisation of a Novel Steroid Sulfatase-Deficient Mouse.Genes, brain, and behavior · 2026Article
- Maternal opioid use disorder and hepatitis C infection in pregnancy reshape the peripheral immune landscape at term.EBioMedicine · 2026Article
- Prenatal exposure to air pollution and the development of autism spectrum disorder from birth to adolescence: A nationwide Danish cohort study.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Advanced maternal age and assisted reproductive technologies: outcomes, genomics, and real-world evidence.Frontiers in reproductive health · 2026Review
- Parkinson's Spectrum Mechanisms in Pregnancy: Exploring Hypothetical Scenarios for MSA in the Era of ART.International journal of molecular sciences · 2025Review
- PD-1-Enhanced Treg Cell Senescence in Advanced Maternal Age.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A Prospective Assessment of the Etiology of Murine Dystocia.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- Prenatal gene-environment interactions mediate the impact of advanced maternal age on mouse offspring behavior.Scientific reports · 2024Article
- Exposure to gestational diabetes mellitus increases subclinical inflammation mediated in part by obesity.Clinical and experimental immunology · 2024Article
- Colonisation of Group BBMJ open · 2023Article
- The Associations of Maternal Health Characteristics, Newborn Metabolite Concentrations, and Child Body Mass Index among US Children in the ECHO Program.Metabolites · 2023Article
- Parental Programming of Offspring Health: The Intricate Interplay between Diet, Environment, Reproduction and Development.Biomolecules · 2022Review
- IL-22 Plays a Dual Role in the Amniotic Cavity: Tissue Injury and Host Defense against Microbes in Preterm Labor.Journal of immunology (Baltimore, Md. : 1950) · 2022Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Women who conceive at 35 years of age or older, commonly known as advanced maternal age, have a higher risk of facing parturition complications and their children have an increased risk of developing diseases later in life. However, the immunological mechanisms underlying these pathological processes have yet to be established. To fill this gap in knowledge, using a murine model and immunophenotyping, we determined the effect of advanced maternal age on the main cellular branch of adaptive immunity, T cells, at the maternal-fetal interface and in the offspring. We report that advanced maternal age impaired the process of labor at term, inducing dystocia and delaying the timing of delivery. Advanced maternal age diminished the number of specific proinflammatory T-cell subsets [T helper type 1 (Th1): CD4
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.