Evidence map›Paper›PMID 32279317›Full record

ArticleMedical physics2020

MR-based PET attenuation correction using a combined ultrashort echo time/multi-echo Dixon acquisition.

Paul Kyu Han, Debra E Horng, Kuang Gong, Yoann Petibon, Kyungsang Kim, Quanzheng Li, Keith A Johnson, Georges El Fakhri, Jinsong Ouyang, Chao Ma

Abstract read
In one paragraph

Article in Medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. MR-based Attenuation Correction for Brain PET Using 3D Cycle-Consistent Adversarial Network.IEEE transactions on radiation and plasma medical sciences · 2021
    Article
  9. Article
  10. Attenuation correction for human PET/MRI studies.Physics in medicine and biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Paul Kyu HanDepartment of Radiology, Gordon Center for Medical Imaging, Massachusetts General Hospital, Boston, MA, 02114, USA.
Debra E HorngDepartment of Radiology, Gordon Center for Medical Imaging, Massachusetts General Hospital, Boston, MA, 02114, USA.
Kuang GongDepartment of Radiology, Gordon Center for Medical Imaging, Massachusetts General Hospital, Boston, MA, 02114, USA.
Yoann PetibonDepartment of Radiology, Gordon Center for Medical Imaging, Massachusetts General Hospital, Boston, MA, 02114, USA.
Kyungsang KimDepartment of Radiology, Gordon Center for Medical Imaging, Massachusetts General Hospital, Boston, MA, 02114, USA.
Quanzheng LiDepartment of Radiology, Gordon Center for Medical Imaging, Massachusetts General Hospital, Boston, MA, 02114, USA.
Keith A JohnsonDepartment of Radiology, Gordon Center for Medical Imaging, Massachusetts General Hospital, Boston, MA, 02114, USA.
Georges El FakhriDepartment of Radiology, Gordon Center for Medical Imaging, Massachusetts General Hospital, Boston, MA, 02114, USA.
Jinsong OuyangDepartment of Radiology, Gordon Center for Medical Imaging, Massachusetts General Hospital, Boston, MA, 02114, USA.
Chao MaDepartment of Radiology, Gordon Center for Medical Imaging, Massachusetts General Hospital, Boston, MA, 02114, USA.

Funding

Unified Joint Statistical Reconstruction of PET & MRP41EB022544 · NIBIB · YALE UNIVERSITY · PI Georges El Fakhri · 2017 to 2026
$14.8M
Quantitative Oncologic PET-MRR01CA165221 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI EL FAKHRI, GEORGES · 2012 to 2023
$4.7M
Postgraduate Training Program in Medical Imaging (PTPMI)T32EB013180 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Ciprian Catana, Pedram Heidari · 2011 to 2026
$3.7M
Quantitative Simultaneous Cardiac PET-MRR01HL118261 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI OUYANG, JINSONG · 2014 to 2018
$2.6M
Study of Brain Spreading Pathways of Tau and Amyloid-Beta in (pre)clinical ADRF1AG052653 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI LI, QUANZHENG, SEPULCRE, JORGE · 2017 to 2017
$1.4M
PET/MRS guided radiotherapyR21EB021710 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI EL FAKHRI, GEORGES · 2016 to 2017
$470k
PROTON THERAPY RESEARCH AND TREATMENT CENTERC06CA059267 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI GOITEIN, MICHAEL · 1992 to 1995
–
Massachusetts General HospitalNCI NIH HHS C06 CA059267NCI NIH HHS R01 CA165221NHLBI NIH HHS R01 HL118261NIA NIH HHS RF1 AG052653NIBIB NIH HHS P41 EB022544NIBIB NIH HHS R21 EB021710NIBIB NIH HHS T32 EB013180NIH HHS C06CA059267NIH HHS P41EB022544NIH HHS R01CA165221NIH HHS R01HL118261NIH HHS R21EB021710NIH HHS T32EB013180
6 · The paper itself

Abstract

purposeTo develop a magnetic resonance (MR)-based method for estimation of continuous linear attenuation coefficients (LACs) in positron emission tomography (PET) using a physical compartmental model and ultrashort echo time (UTE)/multi-echo Dixon (mUTE) acquisitions.

methodsWe propose a three-dimensional (3D) mUTE sequence to acquire signals from water, fat, and short T

resultsThe performance of the proposed method was evaluated via phantom and in vivo human studies, using LACs from computed tomography (CT) as reference. Compared to Dixon- and atlas-based MRAC methods, the proposed method yielded PET images with higher correlation and similarity in relation to the reference. The relative absolute errors of PET activity values reconstructed by the proposed method were below 5% in all of the four lobes (frontal, temporal, parietal, and occipital), cerebellum, whole white matter, and gray matter regions across all subjects (n = 6).

conclusionsThe proposed mUTE method can generate subject-specific, continuous LAC map for PET attenuation correction in PET/MR.

Indexed as

Image Processing, Computer-AssistedPositron-Emission TomographyHumansMagnetic Resonance ImagingPhantoms, ImagingTomography, X-Ray Computedcontinuous LACMRACMR-based attenuation correctionmulti-echo DixonPET attenuation correctionPET/MRultrashort echo time (UTE)

Identifiers

PMID32279317
PMCPMC7375929

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.