Evidence map›Paper›PMID 32279243›Full record

ArticleAging clinical and experimental research2021

Inflammation, pressure ulcers and poor functional status predict negative rehabilitation outcomes in postacute geriatric patients.

Roberto Aquilani, Ginetto Carlo Zuccarelli, Roberto Maestri, Carla Rutili, Mauro Colombo, Anna Maria Condino, Annalisa Barbieri, Alessandra Cecchetti, Simona Vanzati, Edi Bonazza and 5 more

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In one paragraph

Article in Aging clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Roberto AquilaniDipartimento di Biologia e Biotecnologie, Università degli Studi di Pavia, via Ferrata 1, 27100, Pavia, Italy.
Ginetto Carlo ZuccarelliReparti di Riabilitazione Geriatrica e di Mantenimento, Istituto Geriatrico P. Redaelli, via Leopardi 3 Vimodrone, 20090, Milano, Italy.
Roberto MaestriDepartment of Biomedical Engineering, Istituti Clinici Scientifici Maugeri IRCCS, Pavia, Italy.
Carla RutiliReparti di Riabilitazione Geriatrica e di Mantenimento, Istituto Geriatrico P. Redaelli, via Leopardi 3 Vimodrone, 20090, Milano, Italy.
Mauro ColomboReparti di Riabilitazione Geriatrica e di Mantenimento, Istituto Geriatrico P. Redaelli, via Leopardi 3 Vimodrone, 20090, Milano, Italy.
Anna Maria CondinoDipartimento di Scienze del Farmaco, Università Degli Studi di Pavia, Viale Taramelli 12, 27100, Pavia, Italy.
Annalisa BarbieriDipartimento di Scienze del Farmaco, Università Degli Studi di Pavia, Viale Taramelli 12, 27100, Pavia, Italy.
Alessandra CecchettiReparti di Riabilitazione Geriatrica e di Mantenimento, Istituto Geriatrico P. Redaelli, via Leopardi 3 Vimodrone, 20090, Milano, Italy.
Simona VanzatiReparti di Riabilitazione Geriatrica e di Mantenimento, Istituto Geriatrico P. Redaelli, via Leopardi 3 Vimodrone, 20090, Milano, Italy.
Edi BonazzaReparti di Riabilitazione Geriatrica e di Mantenimento, Istituto Geriatrico P. Redaelli, via Leopardi 3 Vimodrone, 20090, Milano, Italy.
Franco LafiandraReparti di Riabilitazione Geriatrica e di Mantenimento, Istituto Geriatrico P. Redaelli, via Leopardi 3 Vimodrone, 20090, Milano, Italy.
Daniela BuonocoreDipartimento di Biologia e Biotecnologie, Università degli Studi di Pavia, via Ferrata 1, 27100, Pavia, Italy.
Manuela VerriDipartimento di Biologia e Biotecnologie, Università degli Studi di Pavia, via Ferrata 1, 27100, Pavia, Italy.
Maurizia DossenaDipartimento di Biologia e Biotecnologie, Università degli Studi di Pavia, via Ferrata 1, 27100, Pavia, Italy.
Federica BoschiDipartimento di Scienze del Farmaco, Università Degli Studi di Pavia, Viale Taramelli 12, 27100, Pavia, Italy. federica.boschi@unipv.it.
University of Pavia · ITIstituti Clinici Scientifici Maugeri · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purposes of this retrospective study were to document the prevalence of serum C-reactive protein (CRP), a biomarker of inflammation, and its potential predictive value for Rehabilitation outcomes in post-acute elderly inpatients. The medical records of 304 elderly subjects admitted to our Rehabilitation Institute for any disease following an acute event were examined. High levels of CRP (> 0.5 mg/dl) were present in 100% of the subjects, and the value > 1.5 mg/dl (n = 86) predicted unfavourable outcomes (n = 28; 32.5% of the patients: death or transfer to other institutions). Among the patients with favourable outcomes (discharge home n = 255), 62.7% still exhibited severe disabilities. Pressure ulcers and low functional status also predicted unfavourable outcomes. The study highlights the need for future investigations into the possible reduction of CRP levels, after an intensive nutritional approach and combined physical interventions.

Indexed as

Pressure UlcerAgedFunctional StatusHumansInflammationRetrospective StudiesTreatment OutcomeC-Reactive proteinDisabilityElderlyOutcomesRehabilitation

Identifiers

PMID32279243
OpenAlexW3015866939

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.