Evidence map›Paper›PMID 32279206›Full record

ArticleJournal of natural medicines2020

Quassilactones A and B, structural characterization of a new class of norquassinoids from Brucea javanica.

Zhiwei Su, Zhonghui Ma, Kai Liu, Tingting Li, Bo Zhou

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of natural medicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Quassinoids as Promising Anti-cancer Agents.Current medicinal chemistry · 2025
    Review
  4. Article
  5. A review ofFrontiers in pharmacology · 2023
    Review
  6. Major Constituents FromFrontiers in pharmacology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhiwei SuInstitute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning, 530200, China.
Zhonghui MaNational Demonstration Center for Experimental Plant Science Education, Agricultural College, Guangxi University, Nanning, 530004, China. mazhonghui@gxu.edu.cn.ORCID http://orcid.org/0000-0002-3898-3079
Kai LiuInstitute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning, 530200, China.
Tingting LiInstitute of Marine Drugs, Guangxi University of Chinese Medicine, Nanning, 530200, China.
Bo ZhouGuangxi Key Laboratory of AIDS Prevention and Treatment and Guangxi Universities Key Laboratory of Prevention and Control of Highly Prevalent Disease, School of Public Health, Guangxi Medical University, Nanning, 530021, China.

Funding

National Natural Science Foundation of China 31760045National Natural Science Foundation of China 81860655Natural Science Foundation of Guangxi Province 2015GXNSFBA139026Natural Science Foundation of Guangxi Province 2018GXNSFAA281132Natural Science Foundation of Guangxi Province 2018GXNSFAA281146
6 · The paper itself

Abstract

Two novel norquassinoids possessing a unique ketal skeleton, designated quassilactones A (1) and B (2), were isolated from the fruits of Brucea javanica (Simaroubaceae). Their structures were established by extensive NMR and HR-ESI-MS spectroscopic analysis. The absolute configuration of 1 was determined through single-crystal X-ray crystallography, and that of 2 was assigned by comparing the calculated electronic and experimental circular dichroism with compound 1. In addition, their cytotoxic activities against three human cancer cell lines and their antimicrobial activities were evaluated.

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsBacteriaBruceaCell LineCrystallography, X-RayFruitHumansMolecular StructureNeoplasmsPlant ExtractsQuassinsAnti-Bacterial AgentsAntineoplastic AgentsPlant ExtractsquassilactoneQuassinsBrucea javanicaNorquassinoidQuassilactoneX-ray crystallography

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.