ArticleJACC. Heart failure2020
Heart Failure Outcomes and Associated Factors Among Veterans With Human Immunodeficiency Virus Infection.
Article in JACC. Heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Clinical Outcomes After Acute Coronary Syndromes or Revascularization Among People Living With HIV: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- Heart Failure Risk and Events in People With HIV: The Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE).Circulation. Heart failure · 2026Trial
- Heart Failure Risk in HIV: From Immunodeficiency to Metabolic Complexity.Circulation. Heart failure · 2026Article
- Major adverse cardiovascular events, morbidity, and mortality, among people living with and without HIV in two northern Uganda hospitals.BMC infectious diseases · 2026Article
- A novel plasma proteomic signature predicts long-term incident heart failure risk among persons living with HIV.medRxiv : the preprint server for health sciences · 2026Article
- Thirty-Day Readmission Risk Among Adults Hospitalized for Heart Failure or Acute Myocardial Infarction With and Without HIV.Open forum infectious diseases · 2025Article
- HIV-Associated Heart Failure: Phenotypes and Clinical Outcomes in a Safety-Net Setting.Journal of the American Heart Association · 2024Article
- Cardiology Encounters for Underrepresented Racial and Ethnic Groups with Human Immunodeficiency Virus and Borderline Cardiovascular Disease Risk.Journal of racial and ethnic health disparities · 2024Article
- HIV-Associated Heart Failure: Phenotypes and Clinical Outcomes in a Safety-Net Setting.medRxiv : the preprint server for health sciences · 2024Article
- Two decade trends in cardiovascular disease outcomes and cardiovascular risk factors among US veterans living with HIV.International journal of cardiology. Cardiovascular risk and prevention · 2022Article
- Human Immunodeficiency Virus Infection-Associated Cardiomyopathy and Heart Failure.Journal of personalized medicine · 2022Review
- Prevention of heart failure, tachyarrhythmias and sudden cardiac death in HIV.Current opinion in HIV and AIDS · 2022Review
- Mortality and length of stay among HIV patients hospitalized for heart failure: A multicenter retrospective study.American heart journal plus : cardiology research and practice · 2022Article
- Age at Diagnosis of Heart Failure in United States Veterans With and Without HIV Infection.Journal of the American Heart Association · 2021Article
- Secondary Prevention of Myocardial Infarction in People Living With HIV Infection.Journal of the American Heart Association · 2020Article
Corrections and comments
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Authors and funding
12 authors at 7 institutions in 1 country.
Funding
Abstract
objectivesThis study sought to investigate outcomes of heart failure (HF) in veterans living with human immunodeficiency virus (HIV).
backgroundData on outcomes of HF among people living with human immunodeficiency virus (PLHIV) are limited.
methodsWe performed a retrospective cohort study of Veterans Health Affairs data to investigate outcomes of HF in PLHIV. We identified 5,747 HIV+ veterans with diagnosis of HF from 2000 to 2018 and 33,497 HIV- frequency-matched controls were included. Clinical outcomes included all-cause mortality, HF hospital admission, and all-cause hospital admission.
resultsCompared with HIV- veterans with HF, HIV+ veterans with HF were more likely to be black (56% vs. 14%), be smokers (52% vs. 29%), use alcohol (32% vs. 13%) or drugs (37% vs. 8%), and have a higher comorbidity burden (Elixhauser comorbidity index 5.1 vs. 2.6). The mean ejection fraction (EF) (45 ± 16%) was comparable between HIV+ and HIV- veterans. HIV+ veterans with HF had a higher age-, sex-, and race-adjusted 1-year all-cause mortality (30.7% vs. 20.3%), HF hospital admission (21.2% vs. 18.0%), and all-cause admission (50.2% vs. 38.5%) rates. Among veterans with HIV and HF, those with low CD4 count (<200 cells/ml) and high HIV viral load (>75 copies/μl) had worse outcomes. The associations remained statistically significant after adjusting for extensive list of covariates. The incidence of all-cause mortality and HF admissions was higher among HIV+ veterans with ejection fraction <45%
conclusionsHIV+ veterans with HF had higher risk of hospitalization and mortality compared with their HIV- counterparts, with worse outcomes reported for individuals with lower CD4 count, higher viral load, and lower ejection fraction.
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Registered trials
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