Evidence map›Paper›PMID 32278175›Full record

ReviewThe Science of the total environment2020

COVID-19: A promising cure for the global panic.

Balachandar Vellingiri, Kaavya Jayaramayya, Mahalaxmi Iyer, Arul Narayanasamy, Vivekanandhan Govindasamy, Bupesh Giridharan, Singaravelu Ganesan, Anila Venugopal, Dhivya Venkatesan, Harsha Ganesan and 5 more

Open access · greenAbstract readReview
In one paragraph

Review in The Science of the total environment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 242 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
242citing papers in PubMed, 7 pooled it
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

242 citing papers in PubMed, 7 syntheses or guidelines pooled it, 651 citations in OpenAlex.

  1. Pooled it
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  5. Compounds of plants with activity against SARS-CoV-2 targets.Expert review of clinical pharmacology · 2021
    Pooled it
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  7. The effect of latitude and PMEnvironmental pollution (Barking, Essex : 1987) · 2020
    Pooled it
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  14. The Antiviral and Antimalarial Prodrug Artemisinin from theCurrent issues in molecular biology · 2024
    Review
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182 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 3 countries.

Balachandar VellingiriHuman Molecular Cytogenetics and Stem Cell Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India. Electronic address: geneticbala@buc.edu.in.
Kaavya JayaramayyaDepartment of Zoology, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore 641 043, Tamil Nadu, India.
Mahalaxmi IyerDepartment of Zoology, Avinashilingam Institute for Home Science and Higher Education for Women, Coimbatore 641 043, Tamil Nadu, India.
Arul NarayanasamyDisease Proteomics Laboratory, Department of Zoology, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India.
Vivekanandhan GovindasamyFarmer's Bio Fertilizers and Organics, Coimbatore 641 029, Tamil Nadu, India.
Bupesh GiridharanVirology Laboratory, Central Research and Development Wing, Sree Balaji Medical College and Hospital (SBMCH), Bharath University, (BIHER), Chromepet, Chennai 600044, Tamil Nadu, India; Department of Forest Science, Central University of Nagaland, Lumami, Zunhebeto, India.
Singaravelu GanesanDepartment of Zoology, Thiruvalluvar University, Vellore 632115, India.
Anila VenugopalHuman Molecular Cytogenetics and Stem Cell Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India.
Dhivya VenkatesanHuman Molecular Cytogenetics and Stem Cell Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India.
Harsha GanesanHuman Molecular Cytogenetics and Stem Cell Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India.
Kamarajan RajagopalanHuman Molecular Cytogenetics and Stem Cell Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore 641 046, Tamil Nadu, India.
Pattanathu K S M RahmanDeploy Lead - Centre for Enzyme Innovation, Office No: 6.06, King Henry Building School of Biological Science, University of Portsmouth, Portsmouth PO1 2DY, UK.
Ssang-Goo ChoDepartment of Stem Cell and Regenerative Biotechnology, Konkuk University, Seoul, South Korea.
Nachimuthu Senthil KumarDepartment of Biotechnology, Mizoram University (A Central University), Aizawl 796 004, Mizoram, India.
Mohana Devi SubramaniamDepartment of Genetics and Molecular Biology, Vision Research Foundation, Chennai 600 006, India.
Bharathiar University · INAvinashilingam University · INKonkuk University · KRMizoram University · INOil and Natural Gas Corporation (India) · INSree Balaji Dental College and Hospital · INThiruvalluvar University · INUniversity of Portsmouth · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The novel Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, which is the causative agent of a potentially fatal disease that is of great global public health concern. The outbreak of COVID-19 is wreaking havoc worldwide due to inadequate risk assessment regarding the urgency of the situation. The COVID-19 pandemic has entered a dangerous new phase. When compared with SARS and MERS, COVID-19 has spread more rapidly, due to increased globalization and adaptation of the virus in every environment. Slowing the spread of the COVID-19 cases will significantly reduce the strain on the healthcare system of the country by limiting the number of people who are severely sick by COVID-19 and need hospital care. Hence, the recent outburst of COVID-19 highlights an urgent need for therapeutics targeting SARS-CoV-2. Here, we have discussed the structure of virus; varying symptoms among COVID-19, SARS, MERS and common flu; the probable mechanism behind the infection and its immune response. Further, the current treatment options, drugs available, ongoing trials and recent diagnostics for COVID-19 have been discussed. We suggest traditional Indian medicinal plants as possible novel therapeutic approaches, exclusively targeting SARS-CoV-2 and its pathways.

Indexed as

Coronavirus InfectionsPandemicsPneumonia, ViralBetacoronavirusCOVID-19HumansSARS-CoV-2Coronavirus disease 2019 (COVID-19)Indian traditional medicineMechanism of actionSARS-CoV-2Therapeutic approach

Identifiers

PMID32278175
PMCPMC7128376
OpenAlexW3013467637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.