Evidence map›Paper›PMID 32277811›Full record

ArticleBioinformatics (Oxford, England)2020

Portable nanopore analytics: are we there yet?

Marco Oliva, Franco Milicchio, Kaden King, Grace Benson, Christina Boucher, Mattia Prosperi

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. OCTOPUS: Disk-based, Multiplatform, Mobile-friendly Metagenomics Classifier.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. TheFrontiers in microbiology · 2023
    Article
  7. Article
  8. Article
  9. Precision medicine in mood disorders.PCN reports : psychiatry and clinical neurosciences · 2022
    Review
  10. Review
  11. Article
  12. Article
  13. KARGA: Multi-platform Toolkit for... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics · 2021
    Article
  14. PHONI: Streamed Matching Statistics with Multi-Genome References.Proceedings. Data Compression Conference · 2021
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marco OlivaDepartment of Engineering, Roma Tre University, Rome, Italy.
Franco MilicchioDepartment of Engineering, Roma Tre University, Rome, Italy.
Kaden KingDepartment of Computer and Information Science and Engineering.
Grace BensonDepartment of Computer and Information Science and Engineering.
Christina BoucherDepartment of Computer and Information Science and Engineering.
Mattia ProsperiDepartment of Epidemiology, University of Florida, Gainesville, FL 32610, USA.

Funding

Developing Computational Methods for Surveillance of Antimicrobial Resistant AgentsR01AI141810 · NIAID · UNIVERSITY OF FLORIDA · PI BOUCHER, CHRISTINA, PROSPERI, MATTIA · 2019 to 2023
$2.1M
NIAID NIH HHS R01 AI141810
6 · The paper itself

Abstract

motivationOxford Nanopore technologies (ONT) add miniaturization and real time to high-throughput sequencing. All available software for ONT data analytics run on cloud/clusters or personal computers. Instead, a linchpin to true portability is software that works on mobile devices of internet connections. Smartphones' and tablets' chipset/memory/operating systems differ from desktop computers, but software can be recompiled. We sought to understand how portable current ONT analysis methods are.

resultsSeveral tools, from base-calling to genome assembly, were ported and benchmarked on an Android smartphone. Out of 23 programs, 11 succeeded. Recompilation failures included lack of standard headers and unsupported instruction sets. Only DSK, BCALM2 and Kraken were able to process files up to 16 GB, with linearly scaling CPU-times. However, peak CPU temperatures were high. In conclusion, the portability scenario is not favorable. Given the fast market growth, attention of developers to ARM chipsets and Android/iOS is warranted, as well as initiatives to implement mobile-specific libraries. AVAILABILITY AND IMPLEMENTATION: The source code is freely available at: https://github.com/marco-oliva/portable-nanopore-analytics.

Indexed as

NanoporesHigh-Throughput Nucleotide SequencingSequence Analysis, DNASoftware

Identifiers

PMID32277811
PMCPMC7828464

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.