Evidence map›Paper›PMID 32277708›Full record

ArticleBiotechnology and bioengineering2020

Fluorescent indicators for continuous and lineage-specific reporting of cell-cycle phases in human pluripotent stem cells.

Yun Chang, Peter B Hellwarth, Lauren N Randolph, Yufei Sun, Yuxian Xing, Wuqiang Zhu, Xiaojun Lance Lian, Xiaoping Bao

Open access · greenAbstract read
In one paragraph

Article in Biotechnology and bioengineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Imaging developmental cell cycles.Biophysical journal · 2021
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yun ChangDavidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana.
Peter B HellwarthDavidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana.
Lauren N RandolphDepartment of Biomedical Engineering, Huck institutes of the Life Sciences, Department of Biology, Pennsylvania State University, University Park, Pennsylvania.
Yufei SunDavidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana.
Yuxian XingDavidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana.
Wuqiang ZhuDepartment of Cardiovascular Medicine, Physiology and Biomedical Engineering, Mayo Clinic, Scottsdale, Arizona.
Xiaojun Lance LianDepartment of Biomedical Engineering, Huck institutes of the Life Sciences, Department of Biology, Pennsylvania State University, University Park, Pennsylvania.
Xiaoping BaoDavidson School of Chemical Engineering, Purdue University, West Lafayette, Indiana.ORCID 0000-0003-0955-6868
Purdue University West Lafayette · USPennsylvania State University · USMayo Clinic in Arizona · US

Funding

Myocardial Repair with a Novel Engineered Cardiac Muscle PatchR01HL142627 · NHLBI · MAYO CLINIC ARIZONA · PI ZHU, WUQIANG · 2019 to 2022
$1.7M
Stem cell immunoengineering for universal cardiac therapy via CRISPR-Cas9R21EB026035 · NIBIB · PENNSYLVANIA STATE UNIVERSITY, THE · PI LIAN, XIAOJUN · 2018 to 2020
$567k
Myocardial Repair with a Novel Engineered Cardiac Muscle PatchR56HL142627 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ZHU, WUQIANG · 2018 to 2018
$371k
NHLBI NIH HHS R01 HL142627NHLBI NIH HHS R56 HL142627NIBIB NIH HHS R21 EB026035
6 · The paper itself

Abstract

Proper cell-cycle progression is essential for the self-renewal and differentiation of human pluripotent stem cells (hPSCs). The fluorescent ubiquitination-based cell-cycle indicator (FUCCI) has allowed the dual-color visualization of the G

Indexed as

Cell CycleCell LineCRISPR-Cas SystemsGene EditingGenes, ReporterHumansMicroscopy, FluorescencePluripotent Stem CellsUbiquitinationcell cycleCRISPR/Cas9FUCCIgene editingheart regenerationhuman pluripotent stem cells

Identifiers

PMID32277708
PMCPMC7299792
OpenAlexW3015971432

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.