Evidence map›Paper›PMID 32277591›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2020

Fatal outcome in a liver transplant recipient with COVID-19.

Jiao-Feng Huang, Kenneth I Zheng, Jacob George, Hai-Nv Gao, Ru-Nan Wei, Hua-Dong Yan, Ming-Hua Zheng

Open access · hybridAbstract readCase Reports
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 9 pooled it
2.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 9 syntheses or guidelines pooled it, 91 citations in OpenAlex.

  1. Pooled it
  2. Effect of immunosuppression maintenance in solid organ transplant recipients with COVID-19: Systematic review and meta-analysis.Transplant infectious disease : an official journal of the Transplantation Society · 2021
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  10. Article
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  14. Coronavirus Precautions: Experience of High Volume Liver Transplant Institute.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2022
    Article
  15. COVID-19 and the liver: a narrative review of the present state of knowledge.Translational gastroenterology and hepatology · 2022
    Review
  16. Living Donor Liver Transplantation During the COVID-19 Pandemic: an Evolving Challenge.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  17. Review
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  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Jiao-Feng HuangDepartment of Liver Research Center, First Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Kenneth I ZhengNAFLD Research Center, Department of Hepatology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.ORCID 0000-0002-1726-9298
Jacob GeorgeStorr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, Sydney, NSW, Australia.
Hai-Nv GaoDepartment of Infectious Disease, Shulan Hospital Affiliated to Zhejiang Shuren University Shulan International Medical College, Hangzhou, China.
Ru-Nan WeiState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Centre for Infectious Diseases, Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Hua-Dong YanDepartment of Hepatology, Key Laboratory of Diagnosis and Treatment of Digestive System Tumors of Zhejiang Province, Hwamei Hospital, Ningbo No. 2 Hospital, University of Chinese Academy of Sciences, Ningbo, China.
Ming-Hua ZhengNAFLD Research Center, Department of Hepatology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.ORCID 0000-0003-4984-2631
Wenzhou Medical University · CNFujian Medical University · CNNingbo No. 2 Hospital · CNState Key Laboratory of Diagnosis and Treatment of Infectious DiseasesThe University of Sydney · AUZhejiang Shuren University · CN

Funding

High Level Creative Talents from Department of Public Health in Zhejiang ProvinceMedical Health Science and Technology Project of Zhejiang Provincial Health Commission 2018ZD039National Natural Science Foundation of China 81500665Project of New Century 551 Talent Nurturing in WenzhouZhejiang Key Research and Development Plan Emergency Project 2020C03123
6 · The paper itself

Abstract

Liver injury is common in patients with COVID-19, but little is known about its clinical presentation and severity in the context of liver transplant. We describe a case of COVID-19 in a patient who underwent transplant 3 years ago for hepatocellular carcinoma. The patient came to clinic with symptoms of respiratory disease; pharyngeal swabs for severe acute respiratory syndrome coronavirus 2 were positive. His disease progressed rapidly from mild to critical illness and was complicated by several nosocomial infections and multiorgan failure. Despite multiple invasive procedures and rescue therapies, he died from the disease. The management of COVID-19 in the posttransplant setting presents complex challenges, emphasizing the importance of strict prevention strategies.

Indexed as

Liver TransplantationBetacoronavirusCarcinoma, HepatocellularCoronavirus InfectionsCOVID-19Cross InfectionEnd Stage Liver DiseaseFatal OutcomeHepatitis BHumansImmunocompromised HostImmunosuppression TherapyImmunosuppressive AgentsLiver NeoplasmsMaleMiddle AgedImmunosuppressive Agentsclinical research/practiceimmunosuppressantimmunosuppression/immune modulationinfection and infectious agentsinfection and infectious agents - viralliver transplantation/hepatology

Identifiers

PMID32277591
PMCPMC7262021
OpenAlexW3015961153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.