Evidence map›Paper›PMID 32277452›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2020

Nanobiolistics: An Emerging Genetic Transformation Approach.

Francis J Cunningham, Gozde S Demirer, Natalie S Goh, Huan Zhang, Markita P Landry

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Recent Advances in Tomato Gene Editing.International journal of molecular sciences · 2024
    Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Carbon Nanotubes: Smart Drug/Gene Delivery Carriers.International journal of nanomedicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Francis J CunninghamDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA, USA.
Gozde S DemirerDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA, USA.
Natalie S GohDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA, USA.
Huan ZhangDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA, USA.
Markita P LandryDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA, USA. landry@berkeley.edu.
University of California, Berkeley · US

Funding

Single-Molecule Imaging of Biological Trauma:Cytokine-Based Intracellular CommunicationR35GM128922 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI LANDRY, MARKITA · 2019 to 2023
$2.0M
NIGMS NIH HHS R35 GM128922
6 · The paper itself

Abstract

Biolistic delivery of biomolecular cargoes to plants with micron-scale projectiles is a well-established technique in plant biotechnology. However, the relatively large micron-scale biolistic projectiles can result in tissue damage, low regeneration efficiency, and create difficulties for the biolistic transformation of isomorphic small cells or subcellular target organelles (i.e., mitochondria and plastids). As an alternative to micron-sized carriers, nanomaterials provide a promising approach for biomolecule delivery to plants. While most studies exploring nanoscale biolistic carriers have been carried out in animal cells and tissues, which lack a cell wall, we can nonetheless extrapolate their utility for nanobiolistic delivery of biomolecules in plant targets. Specifically, nanobiolistics has shown promising results for use in animal systems, in which nanoscale projectiles yield lower levels of cell and tissue damage while maintaining similar transformation efficiencies as their micron-scale counterparts. In this chapter, we specifically discuss biolistic delivery of nanoparticles for plant genetic transformation purposes and identify the figures of merit requiring optimization for broad-scale implementation of nanobiolistics in plant genetic transformations.

Indexed as

Transformation, GeneticAnimalsBiolisticsGoldNanoparticlesPlantsGoldAgricultureBiolisticsBionanotechnologyCarbon nanotubes (CNTs)Gold nanoparticlesMesoporous silica nanoparticles (MSNs)NanobiolisticsNanoparticlesPlant transformation

Identifiers

PMID32277452
PMCPMC10461872
OpenAlexW3015547335

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.