Evidence map›Paper›PMID 32277441›Full record

ArticleMolecular biology reports2020

AcGly-Phe-Asn(OH) and AcGly-Phe-Asn(NH

Luana Quassinti, Giuseppe Gianfranceschi, Antonio Cipiciani, Andrea Caporale, Menotti Ruvo, Massimo Bramucci

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Luana QuassintiScuola di Scienze del Farmaco e dei Prodotti della Salute, Università di Camerino, via Gentile III da Varano, 1, Camerino, MC, 62032, Italy.
Giuseppe GianfranceschiCentro Studi "Giuseppe Gianfranceschi", Castelplanio, AN, 60031, Italy.
Antonio CipicianiDipartimento di Chimica, Biologia e Biotecnologie, Università di Perugia, via Elce di Sotto, 8, Perugia, 06123, Italy.
Andrea CaporaleIstituto di Biostrutture e Bioimmagini, CNR, via Mezzocannone, 16, Napoli, 80134, Italy.
Menotti RuvoIstituto di Biostrutture e Bioimmagini, CNR, via Mezzocannone, 16, Napoli, 80134, Italy.
Massimo BramucciScuola di Scienze del Farmaco e dei Prodotti della Salute, Università di Camerino, via Gentile III da Varano, 1, Camerino, MC, 62032, Italy. massimo.bramucci@unicam.it.
Institute of Biostructure and Bioimaging · ITUniversità di Camerino · ITOspedale San Giuseppe · ITUniversity of Perugia · IT

Funding

University of Camerino FPI000029
6 · The paper itself

Abstract

There is increasing interest in the bioactivity of peptides carrying out antiproliferative, antihypertensive, antimicrobial, antioxidant, anticholesterolemic, opioid, and antidiabetic activities. The bioavailability of peptides depends on how readily they are digested by endopeptidases and their ability to pass through cell membranes, features that are determined by the peptide's chemical and physical structure. On the basis of structures present in peptides that have biological activity, particularly antiproliferative activity, the tripeptides AcGly-Phe-Asn(OH) and AcGly-Phe-Asn(NH

Indexed as

Amino Acid SequenceBreast NeoplasmsCell Line, TumorCell-Penetrating PeptidesCell ProliferationCell SurvivalHumansOligopeptidesPeptidesStructure-Activity RelationshipCell-Penetrating PeptidesOligopeptidesPeptidesAntiproliferative activityHormesisN-terminal amidationTripeptide

Identifiers

PMID32277441
OpenAlexW3016012613

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.