Evidence map›Paper›PMID 32277432›Full record

ArticleAging clinical and experimental research2021

Swallowing impairment in older adults: association with sensorimotor peripheral nerve function from the Health, Aging and Body Composition study.

Rafaela Soares Rech, Elsa S Strotmeyer, Brittney S Lange-Maia, Fernando Neves Hugo, Bárbara Niegia Garcia de Goulart, Juliana Balbinot Hilgert, Eleanor M Simonsick

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging clinical and experimental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Rafaela Soares RechGraduate Studies Program in Epidemiology, Faculty of Medicine, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil.ORCID https://orcid.org/0000-0002-3207-0180
Elsa S StrotmeyerDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, USA.ORCID https://orcid.org/0000-0002-4093-6036
Brittney S Lange-MaiaDepartment Preventive Medicine, Rush University Medical Center, Chicago, IL, USA.ORCID https://orcid.org/0000-0001-6642-7558
Fernando Neves HugoGraduate Studies Program in Dentistry, Faculty of Dentistry, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil.ORCID https://orcid.org/0000-0003-2222-7719
Bárbara Niegia Garcia de GoulartGraduate Studies Program in Epidemiology, Faculty of Medicine, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil.ORCID http://orcid.org/0000-0002-2502-5883
Juliana Balbinot HilgertGraduate Studies Program in Epidemiology, Faculty of Medicine, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil.ORCID https://orcid.org/0000-0002-2204-1634
Eleanor M SimonsickIntramural Research Program, National Institute on Aging, Harbor Hospital, 3001 S. Hanover Street, Baltimore, MD, 21225, USA. simonsickel@grc.nia.nih.gov.ORCID https://orcid.org/0000-0002-5460-3494
Universidade Federal do Rio Grande · BRMedStar Harbor Hospital · USRush University Medical Center · USUniversidade Federal do Rio Grande do Sul · BRUniversity of Pittsburgh · US

Funding

TRAINING IN THE EPIDEMIOLOGY OF AGINGT32AG000181 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STROTMEYER, ELSA S. · 1989 to 2025
$6.2M
Peripheral Nerve Function Decline in an Aged CohortR01AG028050 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STROTMEYER, ELSA S. · 2007 to 2015
$3.5M
End of Life in the Very OldR01NR012459 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALBERT, STEVEN M, LUNNEY, JUNE R · 2011 to 2015
$2.7M
Intramural NIH HHS Z99 AG999999NIA NIH HHS R01 AG028050NIA NIH HHS T32 AG000181NINR NIH HHS R01 NR012459
6 · The paper itself

Abstract

backgroundThe purpose of this study was to examine whether impairments in sensorimotor peripheral nerve function are associated with a higher likelihood of swallowing impairment in older adults.

methodsHealth, Aging and Body Composition participants (n = 607, age = 75.8 ± 2.7 years, 55.8% women, 32.3% black) underwent peripheral nerve testing at Year 4 and 11 with swallowing difficulty assessed at Year 4 and 15. Nerve conduction amplitude and velocity were measured at the peroneal motor nerve. Sensory nerve function was assessed with the vibration detection threshold and monofilament (1.4-g/10-g) testing at the big toe. Symptoms of lower extremity peripheral neuropathy and difficulty swallowing were collected by self-report. Data analysis was performed using a hierarchical approach. Odds ratios (ORs) were estimated using non-conditional logistic regression.

resultsAt Year 15 108 (17.8%) participants had swallowing impairments. In fully adjusted models, the peripheral nerve impairments associated with swallowing impairment were numbness (OR 4.67; 95%CI 2.24-9.75) and poor motor nerve conduction velocity (OR 2.26; 95%CI 1.08-4.70). Other peripheral nerve impairments were not related to swallowing.

conclusionsThe association between slow motor nerve conduction velocity and numbness and a higher likelihood of swallowing difficulties a decade later in our prospective study identifies an important area for further investigation in older adults.

Indexed as

DeglutitionPeripheral NervesAgedAgingBody CompositionFemaleHumansMaleProspective StudiesAutonomic nervous systemDeglutition disordersOlder adultsPeripheral nervesSwallowingSwallowing difficultiesSwallowing disorders

Identifiers

PMID32277432
PMCPMC8943851
OpenAlexW3015448755

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.