Evidence map›Paper›PMID 32277380›Full record

ReviewMycopathologia2020

Candida Biofilms: An Update on Developmental Mechanisms and Therapeutic Challenges.

Patrícia Pimentel de Barros, Rodnei Dennis Rossoni, Cheyenne Marçal de Souza, Liliana Scorzoni, Juliana De Camargo Fenley, Juliana Campos Junqueira

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mycopathologia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
1.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 91 citations in OpenAlex.

  1. Preventive action of ketamine alone and in combination with antifungals on Candida biofilm formation in catheters.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  2. Microorganisms · 2026
    Review
  3. Article
  4. Article
  5. Antifungal Effects of Pterostilbene onJournal of fungi (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Review
  8. mBio · 2025
    Article
  9. Article
  10. Impact of Biofilm Formation by VaginalJournal of fungi (Basel, Switzerland) · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Synergistic antifungal effect of thiophene derivative as an inhibitor of fluconazole-resistant Candida spp. biofilms.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  17. Article
  18. Article
  19. Review
  20. Exploring the Antibiofilm Effect of Sertraline in Synergy withPharmaceuticals (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Patrícia Pimentel de BarrosDepartment of Biosciences and Oral Diagnosis, São Paulo State University (Unesp), Institute of Science and Technology, São José dos Campos, Avenida Engenheiro Francisco José Longo 777, São Dimas, São José dos Campos, SP, CEP 12245-000, Brazil. barrosdnapp@yahoo.com.br.ORCID http://orcid.org/0000-0003-4885-2811
Rodnei Dennis RossoniDepartment of Biosciences and Oral Diagnosis, São Paulo State University (Unesp), Institute of Science and Technology, São José dos Campos, Avenida Engenheiro Francisco José Longo 777, São Dimas, São José dos Campos, SP, CEP 12245-000, Brazil.ORCID http://orcid.org/0000-0002-9977-3040
Cheyenne Marçal de SouzaDepartment of Biosciences and Oral Diagnosis, São Paulo State University (Unesp), Institute of Science and Technology, São José dos Campos, Avenida Engenheiro Francisco José Longo 777, São Dimas, São José dos Campos, SP, CEP 12245-000, Brazil.
Liliana ScorzoniDepartment of Biosciences and Oral Diagnosis, São Paulo State University (Unesp), Institute of Science and Technology, São José dos Campos, Avenida Engenheiro Francisco José Longo 777, São Dimas, São José dos Campos, SP, CEP 12245-000, Brazil.ORCID http://orcid.org/0000-0002-0178-6653
Juliana De Camargo FenleyDepartment of Biosciences and Oral Diagnosis, São Paulo State University (Unesp), Institute of Science and Technology, São José dos Campos, Avenida Engenheiro Francisco José Longo 777, São Dimas, São José dos Campos, SP, CEP 12245-000, Brazil.
Juliana Campos JunqueiraDepartment of Biosciences and Oral Diagnosis, São Paulo State University (Unesp), Institute of Science and Technology, São José dos Campos, Avenida Engenheiro Francisco José Longo 777, São Dimas, São José dos Campos, SP, CEP 12245-000, Brazil.ORCID http://orcid.org/0000-0001-6646-6856
Universidade Estadual Paulista (Unesp) · BRDepartment of Aerospace Science and Technology · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 306330/2018-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/02652-6Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/19219-3Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/05664-0
6 · The paper itself

Abstract

Fungi of the genus Candida are important etiological agents of superficial and life-threatening infections in individuals with a compromised immune system. One of the main characteristics of Candida is its ability to form highly drug tolerance biofilms in the human host. Biofilms are a dynamic community of multiple cell types whose formation over time is orchestrated by a network of transcription regulators. In this brief review, we provide an update of the processes involved in biofilm formation by Candida spp. (formation, treatment, and control), as well as the transcriptional circuitry that regulates its development and interactions with other microorganisms. Candida albicans is known to build mixed species biofilms with other Candida species and with various other bacterial species in different host niches. Taken together, these properties play a key role in Candida pathogenesis. In addition, this review gathers recent studies with new insights and perspectives for the treatment and control of Candida biofilms.

Indexed as

BiofilmsCandidaCell AdhesionGenome-Wide Association StudyHumansMicroscopy, Electron, ScanningNanotechnologyRegulatory Elements, TranscriptionalAlternative treatmentBiofilmsCandida spp.Polymicrobial biofilmsTranscriptional circuitry

Identifiers

PMID32277380
OpenAlexW3015822807

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.