ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020
Does the EQ-5D-5L benefit from extension with a cognitive domain: Testing a multi-criteria psychometric strategy in trauma patients.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 16 citations in OpenAlex.
- Psychometric validation of a cognition and social participation bolt-on for the EQ-5D-5L in SARS-CoV-2 infected German healthcare workers.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Validity of EQ-5D-5L breathing and cognition bolt-ons in non-hospitalized patients after COVID-19.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Psychometric testing of two respiratory bolt-on items to EQ-5D-5L in patients with obstructive airway diseases.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Testing four cognition bolt-on items to the EQ-5D in a general Chinese population.The European journal of health economics : HEPAC : health economics in prevention and care · 2025Article
- Testing the psychometric characteristics of EQ-5D-5L and respiratory bolt-ons using a sample of the Australian population.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Enhancing EQ-5D-5L Sensitivity in Capturing the Most Common Symptoms in Post-COVID-19 Patients: An Exploratory Cross-Sectional Study with a Focus on Fatigue, Memory/Concentration Problems and Dyspnea Dimensions.International journal of environmental research and public health · 2024Article
- Article
- A hearing bolt-on item increased the measurement properties of the EQ-5D-5L in a community-based hearing loss screening program.The European journal of health economics : HEPAC : health economics in prevention and care · 2023Article
- Observational
- Sensitivity of the EQ-5D-5L for fatigue and cognitive problems and their added value in Q-fever patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Article
- Assessing Health-Related Quality of Life of Adult Patients with Intermediate Burns: The Added Value of an Itching and Cognition Item for the EQ-5D: A Retrospective Observational Study.European burn journal · 2022Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
purposeThis study investigated the psychometric yield of extension of the EQ-5D-5L with a cognitive domain (EQ-5D+C) in a mixed cohort of trauma patients with repeated data.
methodsA stratified sample of patients that presented at the emergency department filled out a follow-up survey 6 and 12 months after trauma. The surveys included the EQ-5D-5L+C, EQ-VAS, and the impact of events scale-revised (IES-R), a validated post-traumatic stress disorder (PTSD) self-assessment scale. Generally, results of the EQ-5D and EQ-5D+C were compared. Psychometrics included the following: distributional features (ceiling/floor effects), discriminatory performance, convergent validity with the EQ-VAS as reference, and responsiveness to change. Psychometric properties were compared between predefined subgroups based on conditions with cognitive impact (Traumatic Brain Injury (TBI)/PTSD).
resultsIn total, 1799 trauma patients responded 6 and 12 months after trauma, including 107 respondents with PTSD, and 273 with TBI. Six months post-trauma, ceiling of the EQ-5D (26.3%) was reduced with 2.2% with the additional cognitive domain. Using EQ-VAS as reference, convergent validity increased slightly with the addition of the cognitive domain: correlation increasing from 0.651 to 0.664. Cognitive level was found to slightly improve over time in TBI (delta: 0.04) and PTSD patients (delta: 0.05), while (almost) no change was found in patients without TBI and PTSD.
conclusionAdding a cognitive domain to the EQ-5D-5L slightly improved measurement properties and better captured change in health status for trauma patients with TBI and PTSD. Inclusion of the cognitive domain in the EQ-5D-5L when measuring in populations with cognitive problems should be considered.
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