Evidence map›Paper›PMID 32277048›Full record

ArticleThe Journal of biological chemistry2020

Assorted dysfunctions of endosomal alkali cation/proton exchanger

Alina Ilie, Annie Boucher, Jaeok Park, Albert Marinus Berghuis, R Anne McKinney, John Orlowski

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The Recycling Endosomal (NaActa physiologica (Oxford, England) · 2026
    Article
  5. Endosomal Mechanisms in Heart Failure Pathophysiology.Current heart failure reports · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Schizophrenia-Linked Protein tSNARE1 Regulates Endosomal Trafficking in Cortical Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  15. Article
  16. Review
  17. Case Report: NovelFrontiers in neurology · 2021
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alina IlieDepartment of Physiology, McGill University, Montreal, Quebec H3G 0B1, Canada.
Annie BoucherDepartment of Physiology, McGill University, Montreal, Quebec H3G 0B1, Canada.
Jaeok ParkDepartment of Biochemistry, McGill University, Montreal, Quebec H3G 0B1, Canada.
Albert Marinus BerghuisDepartment of Biochemistry, McGill University, Montreal, Quebec H3G 0B1, Canada.
R Anne McKinneyDepartment of Pharmacology and Therapeutics, McGill University, Montreal, Quebec H3G 0B1, Canada.
John OrlowskiDepartment of Physiology, McGill University, Montreal, Quebec H3G 0B1, Canada john.orlowski@mcgill.ca.ORCID 0000-0001-7371-175X
McGill University · CA

Funding

CIHR MOP-133611CIHR PJT-155976CIHR PJT-162365
6 · The paper itself

Abstract

Genetic screening has identified numerous variants of the endosomal solute carrier family 9 member A6 (

Indexed as

AtaxiaEndosomesEpilepsyGenetic Diseases, X-LinkedIntellectual DisabilityMicrocephalyMutation, MissenseOcular Motility DisordersSodium-Hydrogen ExchangersAmino Acid SubstitutionAnimalsCricetinaeHeLa CellsHumansHydrogen-Ion ConcentrationProtein DomainsSLC9A6 protein, humanSodium-Hydrogen Exchangersapoptosisendocytosisendosomemembrane transportneurological diseasepH regulationprotein sortingsodium-proton exchangestructure–function

Identifiers

PMID32277048
PMCPMC7242699
OpenAlexW3015383794

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.