Evidence map›Paper›PMID 32276947›Full record

ReviewClinical journal of the American Society of Nephrology : CJASN2020

Toward Patient-Centered Innovation: A Conceptual Framework for Patient-Reported Outcome Measures for Transformative Kidney Replacement Devices.

Jennifer E Flythe, Tandrea S Hilliard, Kourtney Ikeler, San Keller, Debbie S Gipson, Amanda C Grandinetti, Robert J Nordyke, Ronald D Perrone, Prabir Roy-Chaudhury, Mark Unruh and 3 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinical journal of the American Society of Nephrology : CJASN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Patient-centred clinical trial design.Nature reviews. Nephrology · 2022
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jennifer E FlytheDivision of Nephrology and Hypertension, Department of Medicine, University of North Carolina Kidney Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
Tandrea S HilliardAmerican Institutes for Research, Chapel Hill, North Carolina.
Kourtney IkelerAmerican Institutes for Research, Chapel Hill, North Carolina.
San KellerAmerican Institutes for Research, Chapel Hill, North Carolina.
Debbie S GipsonDivision of Nephrology, Department of Pediatrics, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0003-4473-9045
Amanda C GrandinettiKidney Health Initiative Patient and Family Partnership Council, Elmhurst, Illinois.
Robert J NordykeBeta6 Consulting Group, Los Angeles, California.ORCID 0000-0003-2424-7852
Ronald D PerroneDivision of Nephrology, Tufts Medical Center, Boston, Massachusetts.ORCID 0000-0002-4963-1132
Prabir Roy-ChaudhuryDivision of Nephrology and Hypertension, Department of Medicine, University of North Carolina Kidney Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
Mark UnruhSchool of Medicine, University of New Mexico, Albuquerque, New Mexico.
Melissa WestKidney Health Initiative and American Society of Nephrology, Washington, DC.
Fraser BocellCenter for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland.ORCID 0000-0002-2943-2662
Frank P HurstCenter for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, Maryland.ORCID 0000-0001-9184-1814

Funding

Tufts Clinical and Translational Science Institute (Pilot Supplement)UL1TR002544 · NCATS · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2018 to 2022
$50.2M
Kidney Health Initiative is a public-private partnership between the American Society of Nephrology, US Food and Drug Administration and the kidney community.R18FD005283 · FDA · AMERICAN SOCIETY OF NEPHROLOGY, INC. · PI Tod Ramses Ibrahim · 2014 to 2026
$4.6M
Investigating strategies to reduce fluid-related complications among hemodialysis patientsK23DK109401 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FLYTHE, JENNIFER E · 2016 to 2020
$992k
FDA HHS R18 FD005283NCATS NIH HHS UL1 TR002544NIDDK NIH HHS K23 DK109401
6 · The paper itself

Abstract

Individuals with dialysis-dependent kidney failure experience considerable disease- and treatment-related decline in functional status and overall well-being. Despite these experiences, there have been few substantive technological advances in KRT in decades. As such, new federal initiatives seek to accelerate innovation. Historically, integration of patient perspectives into KRT product development has been limited. However, the US Food and Drug Administration recognizes the importance of incorporating patient perspectives into the total product life cycle (

Indexed as

Patient Reported Outcome MeasuresQuality of LifeUser-Centered DesignClinical Trials as TopicEmploymentFatigueHumansInterpersonal RelationsInventionsLeisure ActivitiesMedical Device LegislationRenal Insufficiency, ChronicRenal Replacement TherapySocial Participationclinical trialdialysisend-stage renal diseasehemodialysisinnovationkidneymedical devicesPatient-Centered Carepatient prioritiesPatient Reported Outcome Measurespatient-reported outcomesPublic-Private Sector Partnershipsquality of liferenal dialysisRenal InsufficiencyRenal Replacement TherapyUnited States Food and Drug Administration

Identifiers

PMID32276947
PMCPMC7536748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.