Evidence map›Paper›PMID 32276613›Full record

Trial reportBMC public health2020

Effective methods for reactivating inactive blood donors: a stratified randomised controlled study.

Jian Ou-Yang, Chun-Hua Bei, Hua-Qin Liang, Bo He, Jin-Yan Chen, Yong-Shui Fu

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03366441 (Effective Methods for Reactivating Inactive Blood Donors), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03366441 nacompletednot on this map

Effective Methods for Reactivating Inactive Blood Donors: a Stratified Randomized Controlled Study

TypeinterventionalSponsorGuangzhou Blood CenterRan2016 to 2017Enrolled11,880ConditionsBlood DonorArmsTelephone call, SMS
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Blood supply management during the Covid-19 pandemic: Experience in a tertiary referral hospital in Malaysia.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jian Ou-YangGuangzhou Blood Center, 7th F., 31st Luyuan Rd. Yuexiu Dist, Guangzhou, Guangdong, China.
Chun-Hua BeiGuangzhou Blood Center, 7th F., 31st Luyuan Rd. Yuexiu Dist, Guangzhou, Guangdong, China.
Hua-Qin LiangGuangzhou Blood Center, 7th F., 31st Luyuan Rd. Yuexiu Dist, Guangzhou, Guangdong, China.
Bo HeGuangzhou Blood Center, 7th F., 31st Luyuan Rd. Yuexiu Dist, Guangzhou, Guangdong, China.
Jin-Yan ChenGuangzhou Blood Center, 7th F., 31st Luyuan Rd. Yuexiu Dist, Guangzhou, Guangdong, China.
Yong-Shui FuGuangzhou Blood Center, 7th F., 31st Luyuan Rd. Yuexiu Dist, Guangzhou, Guangdong, China. fuyongshui@sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecruiting of sufficient numbers of donors of blood products is vital worldwide. In this study we assessed the efficacy and cost-effectiveness of telephone calls and SMS reminders for re-recruitment of inactive blood donors.

methodsThis single-centre, non-blinded, parallel randomised controlled trial in Guangzhou, China included 11,880 inactive blood donors whose last donation was between January 1 and June 30, 2014. The donors were randomly assigned to one of two intervention groups (telephone call or short message service [SMS] communications) or to a control group without intervention. SMS messages with altruistic appeal were adopted in the SMS group; in addition to altruistic appeal, reasons for deferral of blood donation were also asked in the telephone group. All participants were followed up for 1 year. The primary outcome was re-donation rate, and rates in different groups were compared by intention-to-treat (ITT) analysis and estimation of the average treatment effect on the treated (ATT). Secondary outcomes were the self-reported deterrents. Other outcomes included the re-donation interval, and the incremental cost-effectiveness ratio (ICER) of telephone calls and SMS reminders on re-recruitment.

resultsITT analysis revealed no significant differences in the re-donation rate among the three groups. ATT estimations indicated that among compliers, telephone calls significantly increased re-donation compared to both SMS reminders and no intervention. Donor return behaviour was positively associated with receiving reminders successfully, being male, older age, and previous donation history. The SMS reminder prompted donors to return sooner than no reminder within 6 months, and according to ICER calculations, SMS reminders were more cost-effective than telephone calls. Donors reported time constraints as the most main causes of self-deferral in the telephone group, and altruistic appeal had a positive effect on these donors.

conclusionsInterventions to reactivate inactive blood donors can be effective, with telephone calls prompting more donors to return but at a greater cost than SMS messages. SMS reminder with altruistic appeal can urge donors to re-donate sooner within 6 months than no reminder.

trial registrationNCT03366441 (Reactivation of Inactive Blood Donors). Retrospectively registered 4 December 2017.

Indexed as

Reminder SystemsTelephoneText MessagingAdultAltruismBlood DonorsChinaCost-Benefit AnalysisFemaleHumansMaleMiddle AgedYoung AdultAltruismBlood donationInactive donorsRecruitmentSelf-reported deterrents

Identifiers

PMID32276613
PMCPMC7147048

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.