Evidence map›Paper›PMID 32276543›Full record

ReviewExperimental biology and medicine (Maywood, N.J.)2020

Three-dimensional models of breast cancer-fibroblasts interactions.

Sunil Singh, Sydnie Tran, Justin Putman, Hossein Tavana

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Experimental biology and medicine (Maywood, N.J.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Unlocking the Therapeutic Potential of Integrin-Linked Kinase Inhibitors in Bioengineered 3D Breast Tumor Stroma Models.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sunil SinghDepartment of Biomedical Engineering, The University of Akron, Akron, OH 44325, USA.
Sydnie TranDepartment of Biomedical Engineering, The University of Akron, Akron, OH 44325, USA.
Justin PutmanDepartment of Biomedical Engineering, The University of Akron, Akron, OH 44325, USA.
Hossein TavanaDepartment of Biomedical Engineering, The University of Akron, Akron, OH 44325, USA.ORCID 0000-0003-3872-1869

Funding

Modeling Treatment-Induced Drug Resistance of Colon Cancer Cells and Treatment StrategiesR15CA216413 · NCI · UNIVERSITY OF AKRON · PI TAVANA, HOSSEIN · 2018 to 2019
$547k
NCI NIH HHS R15 CA216413
6 · The paper itself

Abstract

impact statementTumor stroma plays an important role in progression of cancers to a fatal metastatic disease. Modern treatment strategies are considering targeting tumor stroma to improve outcomes for cancer patients. A current challenge to develop stroma-targeting therapeutics is the lack of preclinical physiologic tumor models. Animal models widely used in cancer research lack human stroma and are not amenable to screening of chemical compounds for cancer drug discovery. In this review, we outline

Indexed as

Breast NeoplasmsCancer-Associated FibroblastsSpheroids, CellularTumor MicroenvironmentCoculture TechniquesFemaleHumansTissue EngineeringTumor Cells, Culturedbreast cancercancer-associated fibroblastsTumor microenvironmenttumor model

Identifiers

PMID32276543
PMCPMC7268931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.