ReviewMolecules (Basel, Switzerland)2020
Main-Chain Phosphorus-Containing Polymers for Therapeutic Applications.
Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Ultralong Hydroxyapatite Nanowires: Promising Flexible Building Blocks for Constructing High-Performance Biomimetic Materials-A Review.Molecules (Basel, Switzerland) · 2026Review
- Advanced Macromolecular Architectures via Inorganic Polymers.Macromolecular rapid communications · 2026Review
- Inorganic Bottlebrush and Comb Polymers as a Platform for Supersoft, Solvent-Free Elastomers.ACS polymers Au · 2024Article
- Superfluorinated, Highly Water-Soluble Polyphosphazenes as PotentialJournal of functional biomaterials · 2024Article
- Amino Acid-Based Polyphosphorodiamidates with Hydrolytically Labile Bonds for Degradation-Tuned Photopolymers.ACS macro letters · 2023Article
- Degradable Bottlebrush Polypeptides and the Impact of their Architecture on Cell Uptake, Pharmacokinetics, and Biodistribution In Vivo.Small (Weinheim an der Bergstrasse, Germany) · 2023Article
- Research Progress in Energy Based on Polyphosphazene Materials in the Past Ten Years.Polymers · 2022Review
- Design, Synthesis and Actual Applications of the Polymers Containing Acidic P-OH Fragments: Part 1. Polyphosphodiesters.International journal of molecular sciences · 2022Review
- Hetero and homo α,ω-chain-end functionalized polyphosphazenes.Journal of polymer science (2020) · 2022Article
- Synthesis of a New Chelating Iminophosphorane Derivative (Phosphazene) for U(VI) Recovery.Polymers · 2022Article
- Recent advances in electrochemical C-H phosphorylation.Frontiers in chemistry · 2022Review
- Intracellular Delivery of Active Proteins by Polyphosphazene Polymers.Pharmaceutics · 2021Article
- Polyphosphazene immunoadjuvants: Historical perspective and recent advances.Journal of controlled release : official journal of the Controlled Release Society · 2021Review
- Biomedical applications of polyphosphazenes.Medical devices & sensors · 2020Article
- Hybrid Porous Microparticles Based on a Single Organosilica Cyclophosphazene Precursor.International journal of molecular sciences · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Polymers in which phosphorus is an integral part of the main chain, including polyphosphazenes and polyphosphoesters, have been widely investigated in recent years for their potential in a number of therapeutic applications. Phosphorus, as the central feature of these polymers, endears the chemical functionalization, and in some cases (bio)degradability, to facilitate their use in such therapeutic formulations. Recent advances in the synthetic polymer chemistry have allowed for controlled synthesis methods in order to prepare the complex macromolecular structures required, alongside the control and reproducibility desired for such medical applications. While the main polymer families described herein, polyphosphazenes and polyphosphoesters and their analogues, as well as phosphorus-based dendrimers, have hitherto predominantly been investigated in isolation from one another, this review aims to highlight and bring together some of this research. In doing so, the focus is placed on the essential, and often mutual, design features and structure-property relationships that allow the preparation of such functional materials. The first part of the review details the relevant features of phosphorus-containing polymers in respect to their use in therapeutic applications, while the second part highlights some recent and innovative applications, offering insights into the most state-of-the-art research on phosphorus-based polymers in a therapeutic context.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.