Evidence map›Paper›PMID 32276490›Full record

Observational studyInternational journal of environmental research and public health2020

Potential Increased Risk of Trisomy 18 Observed After a Fertilizer Warehouse Fire in Brazos County and TX.

Xiaohui Xu, Xiao Zhang, JeongWon Han, Yau Adamu, Bangning Zhang

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaohui XuDepartment of Epidemiology and Biostatistics, School of Public Health, Texas A&M University, 212 12 Adriance Lab Road, College Station, TX 77843, USA.
Xiao ZhangDepartment of Epidemiology and Biostatistics, School of Public Health, Texas A&M University, 212 12 Adriance Lab Road, College Station, TX 77843, USA.
JeongWon HanDepartment of Epidemiology and Biostatistics, School of Public Health, Texas A&M University, 212 12 Adriance Lab Road, College Station, TX 77843, USA.
Yau AdamuDepartment of Epidemiology and Biostatistics, School of Public Health, Texas A&M University, 212 12 Adriance Lab Road, College Station, TX 77843, USA.ORCID 0000-0003-2388-1085
Bangning ZhangDepartment of Epidemiology and Biostatistics, School of Public Health, Texas A&M University, 212 12 Adriance Lab Road, College Station, TX 77843, USA.ORCID 0000-0001-7499-5686

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this paper, we aimed to investigate the potential impacts of a fire accident in a fertilizer warehouse on chromosomal anomalies, including Trisomy 21 (T21) and Trisomy (T18) among pregnancies in Brazos County, Texas. We conducted an observational study in Brazos County, TX, with all patients of T18 and T21 cases in the live births in Brazos County between 2005-2014. The prevalence of T18 and T21 before, during, and after the accident in Brazos County were calculated and compared. The Standardized Morbidity Ratio (SMR) was applied to compare the prevalence of T18 and T21 in Brazos County to the statewide prevalence in Texas after adjusting for maternal race and age. Compared with statewide risk, the risk of T18 during the impacted years in Brazos county was found to be significantly higher (SMR = 5.0, 95% Confidence Interval(CI): 2.19-9.89), while there was no significant difference before (SMR = 0.77, 0.13-2.54) and after the accident (SMR = 0.71, 0.12-2.36). However, the prevalence of T21 during the impacted years was not significantly different from those before or after the accident. This study conclusively suggests that this fertilizer fire may be related to the increased prevalence of T18 in Brazos County, though the findings warrant further investigation.

Indexed as

FertilizersTrisomy 18 SyndromeFemaleHumansPregnancyTexasTrisomyFertilizersbirth defectschromosomal anomaliesfertilizerfiretrisomy

Identifiers

PMID32276490
PMCPMC7177937

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.