Evidence map›Paper›PMID 32276343›Full record

ReviewInternational journal of molecular sciences2020

MiR-144: A New Possible Therapeutic Target and Diagnostic/Prognostic Tool in Cancers.

Omid Kooshkaki, Zohre Rezaei, Meysam Rahmati, Parviz Vahedi, Afshin Derakhshani, Oronzo Brunetti, Amir Baghbanzadeh, Behzad Mansoori, Nicola Silvestris, Behzad Baradaran

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
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  7. The Role of miR-144 in Inflammatory Diseases: A Review.Immunity, inflammation and disease · 2025
    Review
  8. Advanced biomedical research · 2025
    Review
  9. Identification of Tumor SuppressiveInternational journal of molecular sciences · 2024
    Article
  10. Article
  11. Integrating the analysis of human biopsies using post-translational modifications proteomics.Protein science : a publication of the Protein Society · 2024
    Review
  12. Article
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Omid KooshkakiStudent Research Committee, Birjand University of Medical Sciences, Birjand 9717853577, Iran.ORCID 0000-0002-0398-6587
Zohre RezaeiCellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand 9717853577, Iran.
Meysam RahmatiInfectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz 5166/15731, Iran.
Parviz VahediDepartment of Anatomical Sciences, Maragheh University of Medical Sciences, Maragheh 5165665931, Iran.ORCID 0000-0001-6662-6768
Afshin DerakhshaniImmunology Research Center, Tabriz University of Medical Sciences, Tabriz 5165665811, Iran.ORCID 0000-0002-3243-233X
Oronzo BrunettiMedical Oncology Unit-IRCCS Istituto Tumori "Giovanni Paolo II" of Bari, 70124 Bari, Italy.ORCID 0000-0002-7014-6828
Amir BaghbanzadehImmunology Research Center, Tabriz University of Medical Sciences, Tabriz 5165665811, Iran.
Behzad MansooriDepartment of Cancer and Inflammation Research, Institute for Molecular Medicine, University of Southern Denmark, 5230 Odense, Denmark.
Nicola SilvestrisMedical Oncology Unit-IRCCS Istituto Tumori "Giovanni Paolo II" of Bari, 70124 Bari, Italy.ORCID 0000-0001-7814-7318
Behzad BaradaranImmunology Research Center, Tabriz University of Medical Sciences, Tabriz 5165665811, Iran.ORCID 0000-0002-8642-6795
Tabriz University of Medical Sciences · IRIstituto Tumori Bari · ITBirjand University of Medical Sciences · IRUniversity of Maragheh · IRUniversity of Sistan and Baluchestan · IRUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are small and non-coding RNAs that display aberrant expression in the tissue and plasma of cancer patients when tested in comparison to healthy individuals. In past decades, research data proposed that miRNAs could be diagnostic and prognostic biomarkers in cancer patients. It has been confirmed that miRNAs can act either as oncogenes by silencing tumor inhibitors or as tumor suppressors by targeting oncoproteins. MiR-144s are located in the chromosomal region 17q11.2, which is subject to significant damage in many types of cancers. In this review, we assess the involvement of miR-144s in several cancer types by illustrating the possible target genes that are related to each cancer, and we also briefly describe the clinical applications of miR-144s as a diagnostic and prognostic tool in cancers.

Indexed as

AnimalsBiomarkers, TumorGene Expression Regulation, NeoplasticGenes, NeoplasmHumansMicroRNAsNeoplasmsPrognosisBiomarkers, TumorMicroRNAsMIRN144 microRNA, humancancermicroRNAmiR-144therapeutic target

Identifiers

PMID32276343
PMCPMC7177921
OpenAlexW3015317176

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.