ArticleCurrent biology : CB2020
Evidence for Hierarchical Cognitive Control in the Human Cerebellum.
Article in Current biology : CB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 111 citations in OpenAlex.
- A bias-accounting meta-analytic approach refines and expands the cerebellar behavioral topography.Neuroscience and biobehavioral reviews · 2025Pooled it
- Dual Transcranial Direct Current Stimulation Modulates Hierarchical Functional Network Organization in Post-Stroke Cognitive Impairment: A Randomized Controlled Trial.CNS neuroscience & therapeutics · 2026Trial
- Temporal Pattern-Dependent Cerebellar Involvement in Conflict Processing: An Online Transcranial Magnetic Stimulation Study.Cerebellum (London, England) · 2026Article
- The cerebellum specializes for language even in the absence of contralateral neocortical inputs.bioRxiv : the preprint server for biology · 2026Article
- From metabolic intermediary to neurotransmitter: purinergic signaling in neurophysiology and vulnerability of brain circuits.Bioscience reports · 2026Review
- Task load modulates network interactions between bilateral fronto-parietal and cerebellar areas during verbal working memory.iScience · 2026Article
- Article
- Neural Correlates of Linguistic and Prosodic Processing in Chinese English-as-a-Foreign-Language (EFL) Learners.Journal of psycholinguistic research · 2026Article
- A Functional Resting-State Network Atlas Based on 420 Older Adults with Hypertension.bioRxiv : the preprint server for biology · 2025Article
- The cerebellar components of the human language network.bioRxiv : the preprint server for biology · 2025Article
- Established and Emergent Reading Skills in Adults with Cerebellar Stroke: Evidence of Phonological Alexia.Cerebellum (London, England) · 2025Article
- Optimizing cognitive control through the interaction between stimulation intensity and duration in single-site and dual-site tDCS.Scientific reports · 2025Article
- A bias-accounting meta-analytic approach refines and expands the cerebellar behavioral topography.bioRxiv : the preprint server for biology · 2025Article
- A new vision of the role of the cerebellum in pain processing.Journal of neural transmission (Vienna, Austria : 1996) · 2025Review
- Cerebellocerebral connectivity predicts body mass index: a new open-source Python-based framework for connectome-based predictive modeling.GigaScience · 2025Article
- Dynamic brain states underlying advanced concentrative absorption meditation: A 7-T fMRI-intensive case study.Network neuroscience (Cambridge, Mass.) · 2025Article
- Limited cerebellar gradient extension in temporal lobe epilepsy with dystonic posturing.Epilepsia open · 2024Article
- Plasma pQTL and brain eQTL integration identifies PNKP as a therapeutic target and reveals mechanistic insights into migraine pathophysiology.The journal of headache and pain · 2024Article
- A hierarchical atlas of the human cerebellum for functional precision mapping.Nature communications · 2024Article
- The computational and neural substrates of individual differences in impulsivity under loss framework.Human brain mapping · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
In non-habitual situations, cognitive control aligns actions with both short- and long-term goals. The capacity for cognitive control is tightly tied to the prefrontal cortex, whose expansion in humans relative to other species is thought to support our superior cognitive control. However, the posterolateral cerebellum has also expanded greatly relative to non-human primates and has an organizational structure that mirrors the prefrontal cortex. Nevertheless, cerebellar contributions to cognitive control are poorly understood. Here, we sought to explore whether a functional hierarchical processing framework, applied to the cerebellum, could elucidate cerebellar contributions to cognitive control. Using functional magnetic resonance imaging, we show that a gradient within the posterolateral cerebellum supports cognitive control with motor-adjacent cerebellar sub-regions supporting control of concrete, proximal actions and motor-distal, cerebellar sub-regions supporting abstract, future processing. This gradient was functionally hierarchical, with regions higher in the hierarchy influencing the relationship between regions lower in the hierarchy. This functional hierarchy provides the infrastructure by which context can inform current actions and prepare for future goals. Crucially, this mirrors the hierarchical organization of cognitive control within the prefrontal cortex. Based on these findings, we propose that the cerebellum contains within itself a parallel but separate hierarchical organization that, along with the prefrontal cortex, supports complex cognition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.