Evidence map›Paper›PMID 32275839›Full record

ArticleAmerican journal of respiratory cell and molecular biology2020

Genome-Wide Analysis Reveals Mucociliary Remodeling of the Nasal Airway Epithelium Induced by Urban PM

Michael T Montgomery, Satria P Sajuthi, Seung-Hyun Cho, Jamie L Everman, Cydney L Rios, Katherine C Goldfarbmuren, Nathan D Jackson, Benjamin Saef, Meghan Cromie, Celeste Eng and 7 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Air pollution-induced airway epithelial barrier dysfunction in COPD: a narrative review of mechanisms and therapeutic implications.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Effects of urban PM2.5 on primary sinonasal epithelial cells in individuals with chronic rhinosinusitis.Toxicological sciences : an official journal of the Society of Toxicology · 2026
    Article
  8. Article
  9. Review
  10. Climate Change and the Future of Allergies and Asthma.Current allergy and asthma reports · 2025
    Review
  11. The different response of PMRespiratory research · 2025
    Article
  12. Non-polar components in PMFrontiers in genetics · 2025
    Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Association Between Particulate Matter Exposure and Chronic Rhinosinusitis.Journal of rhinology : official journal of the Korean Rhinologic Society · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Michael T MontgomeryCenter for Genes, Environment, and Health, and.ORCID 0000-0002-6748-2329
Satria P SajuthiCenter for Genes, Environment, and Health, and.
Seung-Hyun ChoRTI International, Research Triangle Park, North Carolina.ORCID 0000-0001-9821-6667
Jamie L EvermanCenter for Genes, Environment, and Health, and.ORCID 0000-0002-1935-4672
Cydney L RiosCenter for Genes, Environment, and Health, and.
Katherine C GoldfarbmurenCenter for Genes, Environment, and Health, and.ORCID 0000-0001-8774-7454
Nathan D JacksonCenter for Genes, Environment, and Health, and.
Benjamin SaefCenter for Genes, Environment, and Health, and.
Meghan CromieCenter for Genes, Environment, and Health, and.
Celeste EngDepartment of Medicine and.
Vivian MedinaCentro de Neumología Pediátrica, San Juan, Puerto Rico; and.
Jennifer R ElhawaryDepartment of Medicine and.ORCID 0000-0003-3326-1680
Sam S OhDepartment of Medicine and.ORCID 0000-0002-2815-6037
Jose Rodriguez-SantanaCentro de Neumología Pediátrica, San Juan, Puerto Rico; and.
Eszter K VladarDivision of Pulmonary Sciences and Critical Care Medicine, Department of Medicine and.ORCID 0000-0002-4160-8894
Esteban G BurchardDepartment of Medicine and.ORCID 0000-0001-7475-2035
Max A SeiboldCenter for Genes, Environment, and Health, and.ORCID 0000-0002-8685-4263
Centro de Neumologia Pediatrica · PRNational Jewish Health · USPulmonary and Critical Care Associates · USRTI International · USUniversity of California, San Francisco · US

Funding

Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1M
The Airway Functional Genomics of Bronchodilator Drug Response in Minority Children with AsthmaR01HL117004 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AHITUV, NADAV, SEIBOLD, MAX A · 2013 to 2022
$9.3M
Transcriptomic and Genetic Endotyping of Exacerbation-Prone AsthmaticsP01HL132821 · NHLBI · NATIONAL JEWISH HEALTH · PI SEIBOLD, MAX A · 2017 to 2021
$9.0M
Social Interventions to address disparities In young adult tobacco useP60MD006902 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BIBBINS-DOMINGO, KIRSTEN · 2012 to 2016
$6.4M
Gene-environments and Admixture in Latino Asthmatics (GALA 2)R01ES015794 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ · 2008 to 2012
$5.4M
SF BUILD: Enabling Students to Represent in ScienceRL5GM118984 · NIGMS · SAN FRANCISCO STATE UNIVERSITY · PI MARQUEZ-MAGANA, LETICIA MARIA, MORRIS, MEGHAN D · 2015 to 2023
$5.2M
Optimizing imputation for diverse populations in a distributed frameworkU01HG009080 · NHGRI · STANFORD UNIVERSITY · PI KENNY, EIMEAR ELIZABETH · 2016 to 2020
$5.2M
Transcriptomic and Pharmacogenetic Asthma Endotypes in Minority ChildrenR01HL135156 · NHLBI · NATIONAL JEWISH HEALTH · PI SEIBOLD, MAX A, ZIV, ELAD · 2017 to 2021
$4.1M
Genes, air pollution, and asthma severity in minority childrenR01MD010443 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEIBOLD, MAX A, ZIV, ELAD · 2016 to 2020
$3.8M
Genetic Control of Airway Epithelium Gene Expression in Childhood AsthmaticsR01HL128439 · NHLBI · NATIONAL JEWISH HEALTH · PI SEIBOLD, MAX A · 2015 to 2019
$3.1M
Poly-omic Study of Asthma Exacerbations in Diverse PopulationsR01HL141845 · NHLBI · HENRY FORD HEALTH SYSTEM · PI WILLIAMS, KEOKI · 2019 to 2022
$3.0M
Integrative Analyses to Uncover Biological Mechanisms Mediating Gene Associations with Asthma Drug Response Among Minority ChildrenR01HL141992 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI BURCHARD, ESTEBAN GONZALEZ, HIMES, BLANCA E · 2018 to 2019
$855k
NCATS NIH HHS UL1 TR001872NHGRI NIH HHS U01 HG009080NHLBI NIH HHS P01 HL132821NHLBI NIH HHS R01 HL117004NHLBI NIH HHS R01 HL128439NHLBI NIH HHS R01 HL135156NHLBI NIH HHS R01 HL141845NHLBI NIH HHS R01 HL141992NIEHS NIH HHS R01 ES015794NIEHS NIH HHS R21 ES024844NIGMS NIH HHS RL5 GM118984NIMHD NIH HHS P60 MD006902NIMHD NIH HHS R01 MD010443NIMHD NIH HHS R56 MD013312
6 · The paper itself

Abstract

Air pollution particulate matter <2.5 μm (PM

Indexed as

Air PollutantsAir PollutionAsthmaGenome-Wide Association StudyHumansInflammationMucin 5ACMucin-5BNasal MucosaParticulate MatterRespiratory MucosaTranscription FactorsAir PollutantsMucin 5ACMucin-5BParticulate MatterTranscription Factorsair pollution particulate matter 2.5airway remodelinghuman nasal airway epitheliummucus metaplasiawhole transcriptome RNA-seq

Identifiers

PMID32275839
PMCPMC7397762
OpenAlexW3015735187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.