ArticleClinical endocrinology2020
Clinical course of adrenal myelolipoma: A long-term longitudinal follow-up study.
Article in Clinical endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 71 citations in OpenAlex.
- Adrenal myelolipoma with severe hemorrhage: a case report.Journal of surgical case reports · 2026Article
- A comprehensive approach to the CT detection and evaluation of large adrenal masses (≥ 4 cm) part 1: benign adrenal lesions.Abdominal radiology (New York) · 2026Review
- Laparoscopic adrenalectomy via transperitoneal and retroperitoneal approaches for bilateral giant adrenal myelolipoma: A case report and literature review.Experimental and therapeutic medicine · 2025Article
- Management of Giant Bilateral Adrenal Myelolipomas in Congenital Adrenal Hyperplasia.JCEM case reports · 2025Article
- Advances in multimodal imaging for adrenal gland disorders: integrating CT, MRI, and nuclear medicine.Japanese journal of radiology · 2025Review
- Bilateral Extra-adrenal Myelolipoma: A Rare Case with Literature Review.Indian journal of surgical oncology · 2025Review
- Spontaneous hemorrhage in adrenal myelolipoma treated with elective laparoscopic adrenalectomy following selective arterial embolization.IJU case reports · 2025Article
- Exploring the Differential Diagnosis of Adrenal Adenoma in the Context of Situs Ambiguous: A Clinical Case Study.Medicina (Kaunas, Lithuania) · 2024Article
- Laparoscopic resection of giant adrenal myelolipoma: A case report with review of literature.Radiology case reports · 2024Article
- Unveiling Pheochromocytoma: A Puzzling Prelude of Nausea, Vomiting, and Abdominal Pain.The American journal of case reports · 2024Article
- Splenic Myelolipomas in the Domestic Cat-To Operate or Not to Operate?Animals : an open access journal from MDPI · 2024Article
- Concurrent adrenal and extra-adrenal myelolipoma: A case report.International journal of surgery case reports · 2024Article
- A Rare Case of Giant Bilateral Adrenal Myelolipomas in a Patient With Classical Congenital Hyperplasia.Cureus · 2024Article
- Bilateral Adrenal Myelolipoma and Breast Cancer in a Patient With Congenital Adrenal Hyperplasia.Cureus · 2024Article
- Review
- Coexistence of Bilateral Giant Adrenal Myelolipomas and Congenital Adrenal Hyperplasia: A Case Report.Cureus · 2023Article
- Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization.Clinical proteomics · 2023Article
- Challenges and controversies in adrenal surgery: A practical approach.Current problems in surgery · 2023Article
- Article
- Etiology, morphology, and outcomes of adrenal calcifications in 540 adult patients-a retrospective single-center study.European journal of endocrinology · 2023Article
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Authors and funding
10 authors at 4 institutions in 3 countries.
Funding
Abstract
objectiveWe aimed to describe clinical course of myelolipoma and to identify predictors of tumour growth and need for surgery.
designA retrospective study. PATIENTS: Consecutive patients with myelolipoma.
resultsA total of 321 myelolipomas (median size, 2.3 cm) were diagnosed in 305 patients at median age of 63 years (range, 25-87). Median follow-up was 54 months. Most myelolipomas were incidentally detected (86%), whereas 9% were discovered during cancer staging and 5% during workup of mass effect symptoms. Thirty-seven (12%) patients underwent adrenalectomy. Compared to myelolipomas <6 cm, tumours ≥6 cm were more likely to be bilateral (21% vs 3%, P < .0001), cause mass effect symptoms (32% vs 0%, P < .0001), have haemorrhagic changes (14% vs 1%, P < .0001) and undergo adrenalectomy (52% vs 5%, P < .0001). Among patients with ≥6 months of imaging follow-up, median size change was 0 mm (-10, 115) and median growth rate was 0 mm/y (-6, 14). Compared to <1 cm growth, ≥1 cm growth correlated with larger initial size (3.6 vs 2.3 cm, P = .02), haemorrhagic changes (12% vs 2%, P = .007) and adrenalectomy (35% vs 8%, P < .0001).
conclusionsMost myelolipomas are incidentally discovered on cross-sectional imaging. Myelolipomas ≥6 are more likely to cause mass effect symptoms, have haemorrhagic changes and undergo resection. Tumour growth ≥1 cm is associated with larger myelolipoma and haemorrhagic changes. Adrenalectomy should be considered in symptomatic patients with large tumours and when there is evidence of haemorrhage or tumour growth.
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