Evidence map›Paper›PMID 32275178›Full record

ArticlePhysiological genomics2020

Harnessing innate immunity to eliminate SARS-CoV-2 and ameliorate COVID-19 disease.

Rachel M Golonka, Piu Saha, Beng San Yeoh, Saurabh Chattopadhyay, Andrew T Gewirtz, Bina Joe, Matam Vijay-Kumar

Abstract readEditorial
In one paragraph

Article in Physiological genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed.

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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rachel M GolonkaUT Microbiome Consortium, Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio.
Piu SahaUT Microbiome Consortium, Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio.
Beng San YeohUT Microbiome Consortium, Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio.ORCID 0000-0002-7723-8733
Saurabh ChattopadhyayDepartment of Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio.
Andrew T GewirtzCenter for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia.
Bina JoeUT Microbiome Consortium, Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio.
Matam Vijay-KumarUT Microbiome Consortium, Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio.ORCID 0000-0002-8732-0167

Funding

Genetic, Epigenetic and Dietary Salt effects on Microbiota and HypertensionR01HL143082 · NHLBI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI JOE, BINA · 2018 to 2021
$2.6M
Interplay between Dietary Fiber and Gut Microbiota in Hepatocellular CarcinomaR01CA219144 · NCI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI VIJAY-KUMAR, MATAM · 2017 to 2021
$1.6M
How Non-transcriptional IRF3 Prevents ALDR21AA026017 · NIAAA · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI CHATTOPADHYAY, SAURABH · 2018 to 2019
$403k
NCI NIH HHS R01 CA219144NHLBI NIH HHS R01 HL143082NIAAA NIH HHS R21 AA026017
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntiviral AgentsApoptosis Regulatory ProteinsBetacoronavirusCalcium-Binding ProteinsChemotherapy, AdjuvantCoronavirus InfectionsCOVID-19Deoxyribonuclease IFlagellinHumansImmunity, InnateInflammationInfluenza A virusInterferon-betaInterleukin-18Antiviral AgentsApoptosis Regulatory ProteinsCalcium-Binding ProteinsCBLB502Deoxyribonuclease IFlagellinInterferon-betaInterleukin-18Ipaf protein, mousePeptidesTLR5 protein, humanToll-Like Receptor 5deoxyribonuclease Iflagellininterferonneutrophil extracellular trapstoll-like receptor 5

Identifiers

PMID32275178
PMCPMC7200864

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.