ArticleJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc2020
In situ hybridization of feline leukemia virus in a primary neural B-cell lymphoma.
Article in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Progressive myelomalacia with spinal cord disorders along with severe intradural hemorrhage in a cat.The Journal of veterinary medical science · 2025Article
- Status Quo of Feline Leukaemia Virus Infection in Turkish Cats and Their Antigenic Prevalence.Animals : an open access journal from MDPI · 2024Article
- Relationship between Uveal Inflammation and Viral Detection in 30 Cats with Feline Infectious Peritonitis.Pathogens (Basel, Switzerland) · 2022Article
- In Situ Hybridization of Feline Leukemia Virus in a Case of Osteochondromatosis.Veterinary sciences · 2022Article
- Primary pulmonary diffuse large B-cell lymphoma associated with feline leukaemia virus infection in a young cat.JFMS open reportsArticle
- Suspected recurrent sarcoma resembling feline injection-site sarcoma with spinal cord invasion in a cat.JFMS open reportsArticle
Corrections and comments
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Authors and funding
9 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An 8-y-old castrated male, outdoor European shorthair cat was presented with a history of hindlimb weakness and paralysis. Disease progression was continuous from the onset; deep algesia disappeared at the final stage. Radiography of the vertebral column was unremarkable; along with patient history and physical examination results, magnetic resonance imaging suggested inflammatory lesions in the spinal cord, although neoplasia could not be ruled out. Feline leukemia virus (FeLV) positivity was confirmed by a serum ELISA prior to euthanasia. Upon postmortem examination, hemorrhages were present in the spinal cord at the level of vertebrae T7-8. Histologic and immunohistochemical analysis revealed primary diffuse large B-cell lymphoma of the spinal cord with multifocal myelomalacia and hemorrhages. To determine the presence of a pathogen within the lesion, we developed a novel in situ hybridization protocol for FeLV (RNAscope). The reaction revealed large amounts of FeLV viral RNA in the tumor cells.
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Registered trials
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