Evidence map›Paper›PMID 32274749›Full record

ReviewAdvances in therapy2020

Emergence Delirium in Perioperative Pediatric Care: A Review of Current Evidence and New Directions.

Ivan Urits, Jacquelin Peck, Stephen Giacomazzi, Riki Patel, John Wolf, Denzil Mathew, Ruben Schwartz, Hisham Kassem, Richard D Urman, Alan D Kaye and 1 more

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Advances in therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07435675 (Efficacy of Ultrasound-guided Greater Auricular Nerve Block in Preventing Postoperative Emergence Agitation in Pediatric Patients Undergoing Microscopic Middle Ear Surgery), which is not on this map. Cited by 61 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 10 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07435675 narecruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy of Ultrasound-guided Greater Auricular Nerve Block in Preventing Postoperative Emergence Agitation in Pediatric Patients Undergoing Microscopic Middle Ear Surgery: A PROSPECTIVE RANDOMIZED DOUBLE- BLINDED CLINICAL TRIAL

TypeinterventionalSponsorFayoum UniversityRan2025 to 2026Enrolled74ConditionsEmergence Agitation, Emergence Delirium, Anesthesia, Emergence From Anesthesia, Emergence DeliriumArmsultrasound-guided greater auricular nerve block (GANB)
3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 10 syntheses or guidelines pooled it, 107 citations in OpenAlex.

  1. Pooled it
  2. Antianxiety effects of dexmedetomidine: systematic review and meta-analysis.European archives of psychiatry and clinical neuroscience · 2026
    Pooled it
  3. Dexmedetomidine Mitigates Sevoflurane-Induced Neurodevelopmental Effects in Paediatric Anaesthesia: A Meta-Analysis and Preclinical Study.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2026
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  12. Application of oral midazolam for preoperative sedation in pediatric tonsillectomy and adenoidectomy and its effects on emergence delirium.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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  14. Determination of the EDDrug design, development and therapy · 2026
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Ivan UritsDepartment of Anesthesia, Critical Care, and Pain Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA. iurits@bidmc.harvard.edu.
Jacquelin PeckDepartment of Anesthesiology, Mount Sinai Medical Center, Miami, FL, USA.
Stephen GiacomazziDepartment of Anesthesiology, Creighton University School of Medicine, Omaha, NE, USA.
Riki PatelDepartment of Anesthesiology, Creighton University School of Medicine, Omaha, NE, USA.
John WolfDepartment of Anesthesiology, Creighton University School of Medicine, Omaha, NE, USA.
Denzil MathewDepartment of Anesthesiology, Creighton University School of Medicine, Omaha, NE, USA.
Ruben SchwartzDepartment of Anesthesiology, Mount Sinai Medical Center, Miami, FL, USA.
Hisham KassemDepartment of Anesthesiology, Mount Sinai Medical Center, Miami, FL, USA.
Richard D UrmanDepartment of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Alan D KayeDepartment of Anesthesiology, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Omar ViswanathDepartment of Anesthesiology, Creighton University School of Medicine, Omaha, NE, USA.
Creighton University · USMount Sinai Medical Center · USBrigham and Women's Hospital · USHarvard University · USLouisiana State University Health Sciences Center New Orleans · USUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emergence delirium (ED) is defined as psychomotor agitation and delirium that typically occurs within 45 min from emergence of anesthesia. Preoperative patient conditions such as anxiety and confusion are risk factors for the development of postoperative ED. Common signs of ED are general non-purposeful resistive movements such as kicking, pulling, flailing as well as lack of eye contact and general lack of awareness of surroundings. The use of volatile anesthetics (VA) is contributory, while the use of total intravenous anesthetic techniques (TIVA) may help to reduce the incidence of emergence delirium. Furthermore, various pharmacologic strategies and alternatively non-pharmacologic strategies have been demonstrated to further diminish its occurrence. The objective of this manuscript is to provide a comprehensive review of anesthetic considerations for pediatric ED and to provide an update on techniques that have been found to be effective in reducing the overall risk of developing postoperative ED in pediatric patients.

Indexed as

AdolescentAnesthesiaAnesthesia Recovery PeriodChildChild, PreschoolEmergence DeliriumFemaleHumansIncidenceInfantInfant, NewbornMalePediatricsPerioperative CarePractice Guidelines as TopicAnesthesiaEmergence agitationEmergence deliriumPediatricsPharmacotherapyPost anesthetic excitement

Identifiers

PMID32274749
OpenAlexW3015924683

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.