Evidence map›Paper›PMID 32274471›Full record

ArticleMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention2019

Invertible Network for Classification and Biomarker Selection for ASD.

Juntang Zhuang, Nicha C Dvornek, Xiaoxiao Li, Pamela Ventola, James S Duncan

Abstract read
In one paragraph

Article in Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Decision Explanation and Feature Importance for Invertible Networks.... IEEE International Conference on Computer Vision workshops. IEEE International Conference on Computer Vision · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Juntang ZhuangBiomedical Engineering, Yale University, New Haven, CT USA.
Nicha C DvornekRadiology & Biomedical Imaging, Yale School of Medicine, New Haven, CT USA.
Xiaoxiao LiBiomedical Engineering, Yale University, New Haven, CT USA.
Pamela VentolaChild Study Center, Yale University, New Haven, CT USA.
James S DuncanBiomedical Engineering, Yale University, New Haven, CT USA.

Funding

Multimodal Developmental Neurogenetics of Females with ASDR01MH100028 · NIMH · YALE UNIVERSITY · PI Allison Elizabeth Jack, LAUREN KENWORTHY · 2012 to 2026
$37.8M
Subnetwork-based Quantitative Imaging Biomarkers for Therapy Assessment in AutismR01NS035193 · NINDS · YALE UNIVERSITY · PI JAMES S DUNCAN, LAWRENCE H. STAIB · 1996 to 2026
$9.2M
NIMH NIH HHS R01 MH100028NINDS NIH HHS R01 NS035193
6 · The paper itself

Abstract

Determining biomarkers for autism spectrum disorder (ASD) is crucial to understanding its mechanisms. Recently deep learning methods have achieved success in the classification task of ASD using fMRI data. However, due to the black-box nature of most deep learning models, it's hard to perform biomarker selection and interpret model decisions. The recently proposed invertible networks can accurately reconstruct the input from its output, and have the potential to unravel the black-box representation. Therefore, we propose a novel method to classify ASD and identify biomarkers for ASD using the connectivity matrix calculated from fMRI as the input. Specifically, with invertible networks, we explicitly determine the decision boundary and the projection of data points onto the boundary. Like linear classifiers, the difference between a point and its projection onto the decision boundary can be viewed as the

Indexed as

ASDbiomarkerinvertible networkregression

Identifiers

PMID32274471
PMCPMC7144624

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.