Evidence map›Paper›PMID 32274464›Full record

ArticleComputational toxicology (Amsterdam, Netherlands)2018

Novel application of normalized pointwise mutual information (NPMI) to mine biomedical literature for gene sets associated with disease: use case in breast carcinogenesis.

Sean M Watford, Rachel G Grashow, Vanessa Y De La Rosa, Ruthann A Rudel, Katie Paul Friedman, Matthew T Martin

Open access · greenAbstract read
In one paragraph

Article in Computational toxicology (Amsterdam, Netherlands), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Sean M WatfordORAU, contractor to U.S. Environmental Protection Agency through the National Student Services Contract, Oak Ridge, TN.
Rachel G GrashowSilent Spring Institute, Newton, MA.
Vanessa Y De La RosaSilent Spring Institute, Newton, MA.
Ruthann A RudelSilent Spring Institute, Newton, MA.
Katie Paul FriedmanCurrently at Pfizer Worldwide Research & Development, Groton, CT, USA.
Matthew T MartinU.S. Environmental Protection Agency, National Center for Computational Toxicology, Research Triangle Park, NC, USA.
Silent Spring Institute · USEnvironmental Protection Agency · USNortheastern University · USPfizer (United States) · USUniversity of North Carolina at Chapel Hill · US

Funding

Transdisciplinary Training at the Intersection of Environmental Health Science and Social Science (EH+SS)T32ES023769 · NIEHS · NORTHEASTERN UNIVERSITY · PI BRODY, JULIA GREEN, BROWN, PHILIP M. · 2015 to 2025
$3.0M
NIEHS NIH HHS T32 ES023769
6 · The paper itself

Abstract

Advances in technology within biomedical sciences have led to an inundation of data across many fields, raising new challenges in how best to integrate and analyze these resources. For example, rapid chemical screening programs like the US Environmental Protection Agency's ToxCast and the collaborative effort, Tox21, have produced massive amounts of information on putative chemical mechanisms where assay targets are identified as genes; however, systematically linking these hypothesized mechanisms with

Indexed as

Biomedical LiteratureBreast CarcinogenesisChemical ExposuresData IntegrationGenesLiterature Mining

Identifiers

PMID32274464
PMCPMC7144681
OpenAlexW2808894064

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.