Evidence map›Paper›PMID 32274455›Full record

ArticleKidney international reports2020

Bleeding Complications After Percutaneous Native Kidney Biopsy: Results From the Boston Kidney Biopsy Cohort.

Ragnar Palsson, Samuel A P Short, Zoe A Kibbelaar, Afolarin Amodu, Isaac E Stillman, Helmut G Rennke, Gearoid M McMahon, Sushrut S Waikar

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 7 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 7 syntheses or guidelines pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. PLA2R autoantibodies, a multifaceted biomarker in nephrotic syndrome and membranous nephropathy.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Kidney biopsy guidebook 2020 in Japan.Clinical and experimental nephrology · 2021
    Guideline
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Performing a percutaneous kidney biopsy.World journal of nephrology · 2026
    Review
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ragnar PalssonRenal Division, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Samuel A P ShortRenal Division, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Zoe A KibbelaarRenal Division, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Afolarin AmoduRenal Division, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Isaac E StillmanDepartment of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Helmut G RennkeDepartment of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Gearoid M McMahonRenal Division, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Sushrut S WaikarRenal Division, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Brigham and Women's Hospital · USBoston University · USBeth Israel Deaconess Medical Center · USNational University Hospital of Iceland · IS

Funding

Harvard Chronic Kidney Disease Research Biopsy CenterUH3DK114915 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI ROSAS, SYLVIA E, WAIKAR, SUSHRUT S. · 2019 to 2021
$900k
6 · The paper itself

Abstract

backgroundThe major risk of kidney biopsy is severe bleeding. Numerous risk factors for bleeding after biopsy have been reported, but findings have been inconsistent.

methodsWe retrospectively reviewed medical records of adult patients enrolled in a native kidney biopsy cohort study to identify major bleeding events (red blood cell [RBC] transfusions, invasive procedures, kidney loss, or death). We used logistic and linear regression models to identify characteristics associated with postbiopsy RBC transfusions and decline in hemoglobin within a week after the procedure.

resultsMajor bleeding events occurred in 28 of 644 (4.3%) patients (28 required an RBC transfusion, 4 underwent angiographic intervention, and 1 had open surgery to control bleeding). No patient lost a kidney or died because of the biopsy. Postbiopsy RBC transfusion risk was driven by the baseline hemoglobin level (odds ratio [OR] 13.6; 95% confidence interval [CI] 5.4-34.1 for hemoglobin <10 vs. ≥10 g/dl). After adjusting for hemoglobin, no other patient characteristics were independently associated with RBC transfusions. Female sex (β = 0.18; 95% CI: 0.04-0.32), estimated glomerular filtration rate (eGFR) <30 ml/min per 1.73 m

conclusionBiopsies were generally well tolerated. Baseline hemoglobin was the dominant risk factor for RBC transfusions, but female sex and eGFR <30 ml/min per 1.73 m

Indexed as

biopsybleedingblood transfusionskidney diseasesrisk factors

Identifiers

PMID32274455
PMCPMC7136322
OpenAlexW3012310731

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.