Evidence map›Paper›PMID 32274390›Full record

ArticleMicrobial cell (Graz, Austria)2020

More than flipping the lid: Cdc50 contributes to echinocandin resistance by regulating calcium homeostasis in

Chengjun Cao, Chaoyang Xue

Open access · goldAbstract readComment
In one paragraph

Article in Microbial cell (Graz, Austria), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chengjun CaoPublic Health Research Institute, New Jersey Medical School, Rutgers University, Newark, NJ USA.
Chaoyang XuePublic Health Research Institute, New Jersey Medical School, Rutgers University, Newark, NJ USA.
Rutgers, The State University of New Jersey · US

Funding

Mechanisms of vaccine protection against AIDS-associated Cryptococcus infectionR01AI141368 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Amariliz Rivera, Chaoyang Xue · 2019 to 2026
$5.4M
The role of inositol in Cryptococcus biology and pathogenesisR01AI123315 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Chaoyang Xue · 2017 to 2026
$5.0M
Lipid flippase in echinocandin drug resistance in Cryptococcus neoformansR21AI154318 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI XUE, CHAOYANG · 2020 to 2021
$430k
NIAID NIH HHS R01 AI123315NIAID NIH HHS R01 AI141368NIAID NIH HHS R21 AI154318
6 · The paper itself

Abstract

Echinocandins are the newest fungicidal drug class approved for clinical use against common invasive mycoses. Yet, they are ineffective against cryptococcosis, predominantly caused by

Indexed as

antifungal drug resistancecalcium/calcineurin signalingCryptococcus neoformanslipid flippase

Identifiers

PMID32274390
PMCPMC7136755
OpenAlexW3011235503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.