Evidence map›Paper›PMID 32274309›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2020

Melanin-Like Nanomaterials for Advanced Biomedical Applications: A Versatile Platform with Extraordinary Promise.

Heng Liu, Youyuan Yang, Yu Liu, Jingjing Pan, Junqing Wang, Fengyuan Man, Weiguo Zhang, Gang Liu

Open access · goldAbstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 188 citations in OpenAlex.

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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Heng LiuDepartment of Radiology PLA Rocket Force Characteristic Medical Center Beijing 100088 China.
Youyuan YangDepartment of Radiology Daping Hospital Army Medical University Chongqing 400042 China.
Yu LiuDepartment of Ultrasound The First Affiliated Hospital Army Medical University Chongqing 400038 China.
Jingjing PanDepartment of Radiology PLA Rocket Force Characteristic Medical Center Beijing 100088 China.
Junqing WangSchool of Pharmaceutical Sciences (Shenzhen) Sun Yat-sen University Guangzhou 510275 China.
Fengyuan ManDepartment of Radiology PLA Rocket Force Characteristic Medical Center Beijing 100088 China.
Weiguo ZhangDepartment of Radiology Daping Hospital Army Medical University Chongqing 400042 China.ORCID https://orcid.org/0000-0003-2622-3686
Gang LiuLaboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine School of Public Health Xiamen University Xiamen 361102 China.ORCID https://orcid.org/0000-0003-2613-7286
Army Medical University · CNAir Force General Hospital PLA · CNSun Yat-sen University · CNXiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Developing efficient, sustainable, and biocompatible high-tech nanoplatforms derived from naturally existing components in living organisms is highly beneficial for diverse advanced biomedical applications. Melanins are nontoxic natural biopolymers owning widespread distribution in various biosystems, possessing fascinating physicochemical properties and playing significant physiological roles. The multifunctionality together with intrinsic biocompatibility renders bioinspired melanin-like nanomaterials considerably promising as a versatile and powerful nanoplatform with broad bioapplication prospects. This panoramic Review starts with an overview of the fundamental physicochemical properties, preparation methods, and polymerization mechanisms of melanins. A systematical and well-bedded description of recent advancements of melanin-like nanomaterials regarding diverse biomedical applications is then given, mainly focusing on biological imaging, photothermal therapy, drug delivery for tumor treatment, and other emerging biomedicine-related implementations. Finally, current challenges toward clinical translation with an emphasis on innovative design strategies and future striving directions are rationally discussed. This comprehensive and detailed Review provides a deep understanding of the current research status of melanin-like nanomaterials and is expected to motivate further optimization of the design of novel tailorable and marketable multifunctional nanoplatforms in biomedicine.

Indexed as

biomedicinemelaninsnanomaterialspolydopaminetheranostics

Identifiers

PMID32274309
PMCPMC7141020
OpenAlexW3005334524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.