Evidence map›Paper›PMID 32274306›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2020

Switching from Fatty Acid Oxidation to Glycolysis Improves the Outcome of Acute-On-Chronic Liver Failure.

Zujiang Yu, Jingjing Li, Zhigang Ren, Ranran Sun, Yang Zhou, Qi Zhang, Qiongye Wang, Guangying Cui, Juan Li, Ang Li and 12 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 26 citations in OpenAlex.

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  11. Glutaminolysis of CD4Journal of inflammation research · 2024
    Review
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  13. Article
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  15. Metabolic regulation of endothelial senescence.Frontiers in cardiovascular medicine · 2023
    Review
  16. Article
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 5 institutions in 2 countries.

Zujiang YuDepartment of Infectious Disease The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052 China.ORCID https://orcid.org/0000-0003-0954-5472
Jingjing LiDepartment of Infectious Disease The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052 China.
Zhigang RenDepartment of Infectious Disease The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052 China.
Ranran SunDepartment of Infectious Disease The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052 China.
Yang ZhouCAS Key Laboratory of Separation Science for Analytical Chemistry Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian 116023 China.
Qi ZhangNeuro-Oncology Branch Center for Cancer Research National Cancer Institute National Institutes of Health Bethesda MD 20892 USA.
Qiongye WangDepartment of Infectious Disease The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052 China.
Guangying CuiDepartment of Infectious Disease The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052 China.
Juan LiDepartment of Infectious Disease The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052 China.
Ang LiDepartment of Infectious Disease The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052 China.
Zhenfeng DuanSarcoma Biology Laboratory Department of Orthopaedic Surgery Massachusetts General Hospital and Harvard Medical School Boston MA 02215 USA.
Yuming XuDepartment of Pharmacy The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052 China.
Zhichao WangCAS Key Laboratory of Separation Science for Analytical Chemistry Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian 116023 China.
Peiyuan YinCAS Key Laboratory of Separation Science for Analytical Chemistry Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian 116023 China.
Hailong PiaoScientific Research Center for Translational Medicine Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian 116023 China.
Jun LvDepartment of Infectious Disease The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052 China.
Xiaorui LiuDepartment of Infectious Disease The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052 China.
Yanfang WangDepartment of Pharmacy The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052 China.
Ming FangMing Fang MD Inc. Walnut Creek CA 94596 USA.
Zhengping ZhuangNeuro-Oncology Branch Center for Cancer Research National Cancer Institute National Institutes of Health Bethesda MD 20892 USA.
Guowang XuCAS Key Laboratory of Separation Science for Analytical Chemistry Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian 116023 China.
Quancheng KanDepartment of Pharmacy The First Affiliated Hospital of Zhengzhou University Zhengzhou 450052 China.
First Affiliated Hospital of Zhengzhou University · CNDalian Institute of Chemical Physics · CNNational Institutes of Health · USHarvard University · USJohn Muir Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute-on-chronic liver failure (ACLF) has a high mortality rate. Metabolic reprogramming is an important mechanism for cell survival. Herein, the metabolic patterns of ACLF patients are analyzed. An in vitro model of ACLF is established using Chang liver cells under hyperammonemia and hypoxia. A randomized clinical trial (ChiCTR-OPC-15006839) is performed with patients receiving

Indexed as

acute‐on‐chronic liver failurehepatocyteshypoxiametabolic reprogramming

Identifiers

PMID32274306
PMCPMC7141014
OpenAlexW3006518088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.