The supraorbital and supratrochlear nerves for ipsilateral corneal neurotization: anatomical study.

Neurotrophic keratitis is a rare corneal disease that is challenging to treat. Corneal neurotization (CN) is among the developing treatments that uses the supraorbital (SON) or supratrochlear (STN) nerve as a donor. Therefore, the goal of this study was to provide the detailed anatomy of these nerves and clarify their feasibility as donors for ipsilateral CN. Both sides of 10 fresh-frozen cadavers were used in this study, and the SON and STN were dissected using a microscope intra- and extraorbitally. The topographic data between the exit points of these nerves and the medial and lateral angle of the orbit were measured, and nerve rotation of these nerves toward the ipsilateral cornea were attempted. The SON and STN were found on 19 of 20 sides. The vertical and horizontal distances between the exit point of the SON and that of the STN, were 7.3±2.1 mm (vertical) and 4.5±2.3 mm, respectively. The mean linear distances between the medial angle and the exit points of each were 22.2±3.0 mm and 14.5±1.9 mm, respectively, and the mean linear distances between the lateral angle and the exit points of the SON and STN were 34.0±2.7 mm and 36.9±2.5 mm, respectively. These nerves rotated ipsilaterally toward the center of the orbit easily. A better understanding of the anatomy of these nerves can contribute to the development and improvement of ipsilateral CN.