Evidence map›Paper›PMID 32274173›Full record

ReviewJournal of thoracic disease2020

Aerobic and breathing exercises improve dyspnea, exercise capacity and quality of life in idiopathic pulmonary fibrosis patients: systematic review and meta-analysis.

Masatoshi Hanada, Karina Tamy Kasawara, Sunita Mathur, Dmitry Rozenberg, Ryo Kozu, S Ahmed Hassan, W Darlene Reid

2 registry-linked trialsOpen access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of thoracic disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 41 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 5 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04946708 nacompletednot on this mapstarted 2021, after this paper: background citation

Using Technology to Engage Patients With Interstitial Lung Disease (ILD) in a Home a Home Exercise Program.

TypeinterventionalSponsorUniversity of ManitobaRan2021 to 2022Enrolled14ConditionsInterstitial Lung DiseaseArmsExercise program (virtual/remote)
NCT05309551 naactive not recruitingnot on this mapstarted 2022, after this paper: background citation

The Effects of Inspiratory Muscle Training Immediatley After Lung Transplantation: a Randomized Controlled Trial

TypeinterventionalSponsorOhio State UniversityRan2022 to 2026Enrolled90ConditionsLung Transplantation, Chronic Lung Disease, Muscle Weakness, RehabilitationArmsIMT- Intervention group, IMT- Placebo group
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 5 syntheses or guidelines pooled it, 85 citations in OpenAlex.

  1. Pooled it
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  3. Exercise and pulmonary embolism: a systematic review of exercise safety, feasibility and effectiveness.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  4. Effect of breathing exercises on patients with interstitial lung disease: A systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Pooled it
  5. Pooled it
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  12. Observational
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  17. Effect of Home-Based Pulmonary Rehabilitation on Pulmonary Fibrosis.Multidisciplinary respiratory medicine · 2024
    Article
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Masatoshi HanadaCardiorespiratory Division, Department of Rehabilitation Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Karina Tamy KasawaraDepartment of Physical Therapy, University of Toronto, Toronto, Canada.
Sunita MathurDepartment of Physical Therapy, University of Toronto, Toronto, Canada.
Dmitry RozenbergDepartment of Medicine, University of Toronto, Canada.
Ryo KozuCardiorespiratory Division, Department of Rehabilitation Medicine, Nagasaki University Hospital, Nagasaki, Japan.
S Ahmed HassanDepartment of Physical Therapy, University of Toronto, Toronto, Canada.
W Darlene ReidDepartment of Physical Therapy, University of Toronto, Toronto, Canada.
University of Toronto · CANagasaki University Hospital · JPToronto Rehabilitation Institute · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIdiopathic pulmonary fibrosis (IPF) is a progressive disease associated with significant dyspnea and limited exercise capacity. This systematic review aimed to synthesize evidence of exercise interventions during pulmonary rehabilitation that aim to improve exercise capacity, dyspnea, and health-related quality of life (HRQL) in IPF patients.

methodsSearches were performed in MEDLINE, Embase, CENTRAL, SPORTDiscus, PubMed and PEDro from inception to January 2019 using search terms for: (I) participants: 'IPF or interstitial lung disease'; (II) interventions: 'aerobic training or resistance training or respiratory muscle training'; and (III) outcomes: 'exercise capacity or dyspnea or health-related quality of life'. Two reviewers independently screened titles, abstracts and full texts to identify eligible studies. Methodological quality of studies was assessed using the Downs and Black checklist and meta-analyses were performed.

resultsOf 1,677 articles identified, 14 were included (four randomized controlled trials and 10 prospective pre-post design studies) that examined 362 patients receiving training and 95 control subjects. Exercise capacity was measured with the 6-minute walk distance, peak oxygen consumption, peak work rate, or endurance time for constant work rate cycling, which increased after exercise [aerobic exercise; aerobic and breathing exercises; aerobic and inspiratory muscle training (IMT) exercises] compared to the control groups. Dyspnea scores improved after aerobic and breathing exercises. HRQL also improved after aerobic exercise training alone or combined with breathing exercises. Aerobic training alone or combined with IMT or breathing exercises improved exercise capacity.

conclusionsBreathing exercises appears to complement exercise training towards improved dyspnea and HRQL in patients with IPF.

Indexed as

Dyspneaexerciseinterstitial lung diseasesquality of liferehabilitation

Identifiers

PMID32274173
PMCPMC7139046
OpenAlexW2999925563

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.