ReviewJournal of thoracic disease2020
Management of anastomotic leaks after esophagectomy and gastric pull-up.
Review in Journal of thoracic disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Outcomes of Gastric Conduit in Corrosive Esophageal Stricture: a Systematic Review and Meta-analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Pooled it
- Challenging esophageal surgery: risk factors, outcomes, and a comparative single-center analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- Evidence-based, cost-effective management of nontraumatic esophageal perforations: An algorithm of the Journal of Trauma and Acute Care Surgery Emergency General Surgery Algorithms Work Group.The journal of trauma and acute care surgery · 2026Article
- Clinical features of Barrett's mucosa arising in the remnant esophagus after subtotal esophagectomy and esophago-gastric anastomosis for esophageal cancer.Esophagus : official journal of the Japan Esophageal Society · 2026Article
- Minimally invasive oesophagectomy for corrosive oesophageal strictures - A single-centre experience from central India.Journal of minimal access surgery · 2026Article
- Does the Dutch trial prove we should "say no" to active surveillance? An in-depth review of the 2025 study on the treatment of esophageal cancer.JTCVS open · 2025Article
- A clinical practice review: management strategies and emerging approaches for anastomotic leakage following radical surgery for esophageal cancer.Annals of palliative medicine · 2025Review
- Feasibility of intraluminal oxygen delivery after minimally invasive esophagus resection.Surgery open science · 2025Article
- Isolation techniques for gastrointestinal tract defects: Two case reports.World journal of gastrointestinal endoscopy · 2025Article
- Addressing Anastomotic Leak After Esophagectomy: Insights from a Specialized Unit.Journal of clinical medicine · 2025Article
- Comprehensive Umbrella Review of the Management of Esophageal Anastomotic Leaks.Journal of clinical medicine · 2025Review
- Endoscopic Treatment of Anastomotic Leakage in the Upper Gastrointestinal Tract.Visceral medicine · 2025Review
- Review
- How to preserve the native or reconstructed esophagus after perforations or postoperative leaks: A multidisciplinary 15-year experience.World journal of gastrointestinal surgery · 2024Article
- The Impact of EndoVAC in Addressing Post-Esophagectomy Anastomotic Leak in Esophageal Cancer Management.Journal of clinical medicine · 2024Review
- Successful Endoscopic Vacuum-Assisted Closure Therapy for Esophageal Perforation: A Case Report.The Korean journal of helicobacter and upper gastrointestinal research · 2024Article
- Endoscopic treatment of nonoperable large postsurgical esophageal fistulas: retrospective analysis of a single tertiary center cohort.iGIE : innovation, investigation and insights · 2024Article
- Minimally invasive treatment of postoperative fistulas, leakages, and perforations of the upper gastrointestinal tract: a single-center observational study.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2023Article
- Diagnosis and management of anastomotic leaks after Ivor Lewis esophagectomy: a single-center experience.Langenbeck's archives of surgery · 2023Article
- A narrative review of anastomotic leak in the Ivor Lewis esophagectomy: expected, accepted, but preventable.Translational cancer research · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anastomotic leak is one of the most feared complications of esophagectomy, leading to prolonged hospital stay, increased postoperative mortality, and additional cost both to the patient and the hospital. Historically, anastomotic leaks have been treated with several techniques including conservative measures, percutaneous or operative drainage, primary surgical repair with buttressing, T-tube drainage, or excision of the esophageal replacement conduit with end esophagostomy. With advances in treatment modalities, including endoscopic stenting, clips and suturing, endoluminal vacuum-assisted closure (EVAC), such leaks increasingly are being managed without operative re-intervention and with salvage of the esophageal replacement conduit. For the purposes of this review, we identified studies analyzing the management of postoperative leak after esophagectomy. We then compared the efficacy of the various newer modalities for closure of anastomotic leaks and gastric conduit defects. We found both esophageal stent and EVAC sponges are effective treatments for closure of anastomotic leak. The chosen treatment modality for salvage of the esophageal replacement conduit is entirely dependent on the patient's clinical status and the surgeon's preference and experience. Emerging endoscopic and endoluminal therapies have increased the armamentarium of tools the esophageal surgeon has to facilitate successful resolution of anastomotic leaks following esophagectomy with reconstruction. While some literature suggests that EVACs have a slightly superior result in conduit success, we question this endorsement as EVACs mostly are utilized for contained leaks, many of which may have healed with conservative measures. This poses a challenge as there is clearly a bias given patient selection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.