Evidence map›Paper›PMID 32274013›Full record

ReviewF1000Research2020

Recent advances in understanding the genetics of sleep.

Maxime Jan, Bruce F O'Hara, Paul Franken

Abstract readReview
In one paragraph

Review in F1000Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Current Evidence for Sleep States inCurrent sleep medicine reports · 2026
    Review
  2. Sleep-Wake Transitions Are Impaired in thebioRxiv : the preprint server for biology · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Brain Clocks, Sleep, and Mood.Advances in experimental medicine and biology · 2021
    Review
  10. Review
  11. Article
  12. Phosphorylation Hypothesis of Sleep.Frontiers in psychology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maxime JanCentre for Integrative Genomics, University of Lausanne, Lausanne, 1015, Switzerland.ORCID 0000-0001-6483-7430
Bruce F O'HaraDepartment of Biology, University of Kentucky, Lexington, 40515, USA.
Paul FrankenCentre for Integrative Genomics, University of Lausanne, Lausanne, 1015, Switzerland.

Funding

SYSTEM FOR AUTOMATED NONINVASIVE MONITORING OF MOUSE SLEEP AND BEHAVIORR44NS083218 · NINDS · SIGNAL SOLUTIONS, LLC · PI LHAMON, MICHAEL E, SUNDERAM, SRIDHAR · 2015 to 2016
$995k
Technology for Non-invasive High-throughput Breath Tracking in RodentsR41HL142489 · NHLBI · SIGNAL SOLUTIONS, LLC · PI O'HARA, BRUCE FREDERICK · 2018 to 2018
$224k
NHLBI NIH HHS R41 HL142489NINDS NIH HHS R44 NS083218
6 · The paper itself

Abstract

Sleep is a ubiquitous and complex behavior in both its manifestation and regulation. Despite its essential role in maintaining optimal performance, health, and well-being, the genetic mechanisms underlying sleep remain poorly understood. Here, we review the forward genetic approaches undertaken in the last four years to elucidate the genes and gene pathways affecting sleep and its regulation. Despite an increasing number of studies and mining large databases, a coherent picture on "sleep" genes has yet to emerge. We highlight the results achieved by using unbiased genetic screens mainly in humans, mice, and fruit flies with an emphasis on normal sleep and make reference to lessons learned from the circadian field.

Indexed as

SleepAnimalsGenetic TestingHumansForward geneticsGeneticsGenetic ScreenGRPGWASSleepSleep Regulation

Identifiers

PMID32274013
PMCPMC7104869

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.