Evidence map›Paper›PMID 32273941›Full record

ArticleOxidative medicine and cellular longevity2020

Bacterial Endotoxin Induces Oxidative Stress and Reduces Milk Protein Expression and Hypoxia in the Mouse Mammary Gland.

Alexander Jonathan Spitzer, Qing Tian, Ratan K Choudhary, Feng-Qi Zhao

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alexander Jonathan SpitzerDepartment of Animal and Veterinary Sciences, University of Vermont, 570 Main Street, Burlington, VT 05452, USA.
Qing TianDepartment of Animal and Veterinary Sciences, University of Vermont, 570 Main Street, Burlington, VT 05452, USA.
Ratan K ChoudharyDepartment of Animal and Veterinary Sciences, University of Vermont, 570 Main Street, Burlington, VT 05452, USA.
Feng-Qi ZhaoDepartment of Animal and Veterinary Sciences, University of Vermont, 570 Main Street, Burlington, VT 05452, USA.ORCID https://orcid.org/0000-0003-4926-670X
University of Vermont · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the mechanisms underlying the reduced milk production during mastitis. We hypothesized that bacterial endotoxin induces hypoxia, oxidative stress, and cell apoptosis while inhibiting milk gene expression in the mammary gland. To test this hypothesis, the left and right sides of the 4

Indexed as

AnimalsCell HypoxiaEndotoxinsEscherichia coliFemaleMammary Glands, AnimalMiceMilk ProteinsOxidative StressEndotoxinsMilk Proteins

Identifiers

PMID32273941
PMCPMC7128054
OpenAlexW3013490823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.