Evidence map›Paper›PMID 32273821›Full record

ArticleReproductive medicine and biology2020

Clinical outcomes of microdissection testicular sperm extraction and intracytoplasmic sperm injection in Japanese men with Y chromosome microdeletions.

Kohei Yamaguchi, Tomomoto Ishikawa, Shimpei Mizuta, Takumi Takeuchi, Hidehiko Matsubayashi, Shoji Kokeguchi, Toshihiro Habara, Kentaro Ichioka, Masakazu Ohashi, Sumihide Okamoto and 9 more

Open access · goldAbstract read
In one paragraph

Article in Reproductive medicine and biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Sperm retrieval, fertilization rates, and clinical outcomes of infertile men with Y chromosome microdeletion A retrospective cohort study.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Double strand DNA breaks in sperm: the bad guy in the crowd.Journal of assisted reproduction and genetics · 2023
    Article
  7. Article
  8. Repetitive DNA Sequences in the Human Y Chromosome and Male Infertility.Frontiers in cell and developmental biology · 2022
    Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 11 institutions in 1 country.

Kohei YamaguchiDivision of Infertility Reproduction Clinic Osaka Osaka Japan.ORCID https://orcid.org/0000-0003-1977-923X
Tomomoto IshikawaDivision of Infertility Reproduction Clinic Osaka Osaka Japan.
Shimpei MizutaDivision of Infertility Reproduction Clinic Osaka Osaka Japan.
Takumi TakeuchiDivision of Infertility Reproduction Clinic Osaka Osaka Japan.
Hidehiko MatsubayashiDivision of Infertility Reproduction Clinic Osaka Osaka Japan.
Shoji KokeguchiHanabusa Womens Central Fertility Clinic Hyogo Japan.
Toshihiro HabaraOkayama Couple's Clinic Okayama Japan.
Kentaro IchiokaIchioka Urological Clinic Kyoto Japan.ORCID https://orcid.org/0000-0002-5395-0240
Masakazu OhashiDepartment of Urology Ogikubo Hospital Tokyo Japan.
Sumihide OkamotoObstetrics and Gynecology ART Okamoto Women's Clinic Nagasaki Japan.ORCID https://orcid.org/0000-0001-8904-3127
Toshihiro KawamuraDenentoshi Ladies Clinic Kanagawa Japan.
Satoru KantoKantou Clinic Miyagi Japan.
Hisanori TaniguchiIVF Namba Clinic Osaka Japan.
Fumiko TawaraTawara IVF Clinic Shizuoka Japan.
Tetsuaki HaraDivision of Reproductive Medicine Hiroshima Prefectural Hospital Hiroshima Japan.
Hatsuki HibiDivision of Urology Kyoritsu General Hospital Aichi Japan.ORCID https://orcid.org/0000-0001-9579-7064
Hiroshi MasudaTesseikai Cranial Nerve Surgery Hospital Osaka Japan.
Takehiko MatsuyamaKoujin Hospital Kagawa Japan.
Hiroaki YoshidaSendai ART Clinic Miyagi Japan.
Osaka Nishi Clinic · JPAkebono Clinic · JPFutaba clinic · JPHiroshima Prefectural Hospital · JPIwaki Kyoritsu General Hospital · JPJapanese Urological Association · JPKoujin Hospital · JPMusashino Art University · JPNagasaki Women's Junior College · JPNational Livestock Breeding Center · JPOgikubo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe investigated the clinical results of Japanese men with Y chromosome microdeletions.

methodsThis study retrospectively examined 2163 azoospermic or severe oligozoospermic patients. We investigated the frequency of azoospermia factor (AZF) deletions and sperm retrieval rate (SRR) by microTESE in patients with these deletions, then analyzed the ICSI outcomes.

resultsAzoospermia factor deletions were found in 201 patients. SRR was significantly higher than that of the control group (74.0% vs 20.4%,

conclusionsOur study highlights that although microTESE in azoospermic men with AZFc microdeletions led to a higher SRR, ICSI outcomes of these men were worse than that of men without AZF deletions, even if testicular spermatozoa were retrieved.

Indexed as

azoospermia factorembryo transferintracytoplasmic sperm injectiontesticular sperm extractionY chromosome microdeletions

Identifiers

PMID32273821
PMCPMC7138942
OpenAlexW3000634478

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.