Evidence map›Paper›PMID 32273698›Full record

ArticleInternational journal of nanomedicine2020

Involvement of TGF-β and ROS in G1 Cell Cycle Arrest Induced by Titanium Dioxide Nanoparticles Under UVA Irradiation in a 3D Spheroid Model.

Yuanyuan Ren, Runqing Geng, Qunwei Lu, Xi Tan, Rong Rao, Hong Zhou, Xiangliang Yang, Wei Liu

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Characterization of Crystalline Phase of TiOMaterials (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yuanyuan RenCollege of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China.ORCID 0000-0002-8145-7162
Runqing GengCollege of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China.
Qunwei LuCollege of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China.
Xi TanCollege of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China.
Rong RaoCollege of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China.
Hong ZhouCollege of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China.
Xiangliang YangCollege of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China.
Wei LiuCollege of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China.
Huazhong University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs one of the most widely produced engineered nanomaterials, titanium dioxide nanoparticles (nano-TiO METHODS AND

resultsIn the present study, the toxicity of nano-TiO

conclusionNano-TiO

Indexed as

AnimalsCell LineCyclin-Dependent Kinase Inhibitor p15Cyclin-Dependent Kinase Inhibitor p21G1 Phase Cell Cycle CheckpointsMiceNanoparticlesReactive Oxygen SpeciesSmad3 ProteinSpheroids, CellularTitaniumTransforming Growth Factor betaUltraviolet RaysCdkn1a protein, mouseCdkn2b protein, mouseCyclin-Dependent Kinase Inhibitor p15Cyclin-Dependent Kinase Inhibitor p21Reactive Oxygen SpeciesSmad3 ProteinSmad3 protein, mouseTitaniumtitanium dioxideTransforming Growth Factor beta3D spheroid culturecell cycle arrestnano-TiO2reactive oxygen speciesTGF-β signaling pathway

Identifiers

PMID32273698
PMCPMC7102912
OpenAlexW3012799024

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.