Evidence map›Paper›PMID 32273682›Full record

Trial reportDrug design, development and therapy2020

Effects of Cisatracurium, Rocuronium, and Mivacurium on Intraocular Pressure During Induction of General Anesthesia in Ophthalmic Surgery.

Shuangshuang Li, Xiao Hu, Fang Tan, Wenxian Li

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Drug design, development and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Antagonist of Chrna1 prevents the pathogenesis of primary focal hyperhidrosis.Annals of clinical and translational neurology · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shuangshuang LiDepartment of Anesthesiology, Eye & ENT Hospital of Fudan University, Shanghai 200031, People's Republic of China.
Xiao HuDepartment of Anesthesiology, Eye & ENT Hospital of Fudan University, Shanghai 200031, People's Republic of China.
Fang Tan *Department of Anesthesiology, Eye & ENT Hospital of Fudan University, Shanghai 200031, People's Republic of China.
Wenxian Li *Department of Anesthesiology, Eye & ENT Hospital of Fudan University, Shanghai 200031, People's Republic of China.
Eye & ENT Hospital of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMaintaining intraocular pressure (IOP) is important in preventing ocular complications in patients undergoing ophthalmic surgery for general anesthesia. The effects of non-depolarizing neuromuscular blockers on IOP remain unclear. The present study compared the effects of cisatracurium, rocuronium, and mivacurium on IOP during induction of general anesthesia in vitreous retinal surgery. MATERIALS AND

methodsIn this prospective randomized double-blinded study, 133 patients undergoing vitreous retinal surgery were randomized into one of the three groups: Group cisatracurium (n=45), Group rocuronium (n=44), or Group mivacurium (n=44). Each drug (cisatracurium 0.1 mg kg

resultsBoth ipsi-operative and control-operative IOP at T1, T2, and T3 significantly decreased from the baseline values (T0) in all three groups (

conclusionBilateral IOP significantly decreased from the baseline values in all three groups during the induction phase. Cisatracurium, rocuronium, and mivacurium did not induce significant changes in bilateral IOP.

Indexed as

Anesthesia, GeneralOphthalmologic Surgical ProceduresAdolescentAdultAgedAtracuriumCorneal InjuriesDiabetic RetinopathyDouble-Blind MethodFemaleHumansIntraocular PressureMaleMiddle AgedMivacuriumProspective StudiesAtracuriumcisatracuriumMivacuriumRocuroniumcisatracuriumgeneral anesthesiaintraocular pressuremivacuriumophthalmic surgeryrocuronium

Identifiers

PMID32273682
PMCPMC7102886
OpenAlexW3012829914

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.