Evidence map›Paper›PMID 32273641›Full record

ArticleNagoya journal of medical science2020

Pathological changes of the myocardium in reworsening of anthracycline-induced cardiomyopathy after explant of a left ventricular assist device.

Hiroaki Hiraiwa, Takahiro Okumura, Shinya Shimizu, Yoshihito Arao, Hideo Oishi, Hiroo Kato, Tasuku Kuwayama, Shogo Yamaguchi, Tomoaki Haga, Tsuyoshi Yokoi and 12 more

Open access · greenAbstract readCase Reports
In one paragraph

Article in Nagoya journal of medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 2 institutions in 1 country.

Hiroaki HiraiwaDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Takahiro OkumuraDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Shinya ShimizuDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yoshihito AraoDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hideo OishiDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hiroo KatoDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Tasuku KuwayamaDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Shogo YamaguchiDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Tomoaki HagaDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Tsuyoshi YokoiDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Toru KondoDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yuki SugiuraDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Naoaki KanoDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Naoki WatanabeDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kenji FukayaDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kenji FurusawaDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Akinori SawamuraDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Ryota MorimotoDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kazuro FujimotoDepartment of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Masato MutsugaDepartment of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Akihiko UsuiDepartment of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Toyoaki MuroharaDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Nagoya University · JPJapanese Red Cross Nagoya Daiichi Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report the long-term changes in cardiac function and pathological findings after successful explantation of a left ventricular assist device in a 42-year-old patient with anthracycline-induced cardiomyopathy with reworsening heart failure. Endomyocardial biopsy samples revealed that the cardiomyocyte diameter decreased and collagen volume fraction increased just after left ventricular assist device explantation. The collagen volume fraction decreased after 6 months, despite preserved systolic function. At 5 years after left ventricular assist device explantation, the systolic function markedly decreased and cardiomyocyte diameter increased. Pathological changes of the myocardium may enable the identification of cardiac dysfunction prior to echocardiographic changes in patients with reworsening heart failure after left ventricular assist device explantation.

Indexed as

Heart-Assist DevicesAdultAntineoplastic Combined Chemotherapy ProtocolsCardiomyopathiesCardiotoxicityDaunorubicinDevice RemovalDisease ProgressionFemaleFibrosisHumansIdarubicinLeukemia, Promyelocytic, AcuteMyocardiumTime FactorsVentricular Function, LeftDaunorubicinIdarubicinanthracycline-induced cardiomyopathycardiac pathologyleft ventricular assist devicereworsening heart failure

Identifiers

PMID32273641
PMCPMC7103868
OpenAlexW3026881110

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.