Evidence map›Paper›PMID 32273638›Full record

ArticleNagoya journal of medical science2020

A comparison of the features of fluorine-18 fluorodeoxyglucose-positron emission tomography (FDG-PET) between IgG4-related disease with bilateral hilar lymphadenopathy and sarcoidosis.

Yoko Ozawa, Hiroshi Yamamoto, Masanori Yasuo, Masamichi Komatsu, Atsuhito Ushiki, Hideaki Hamano, Takeshi Uehara, Satoshi Kawakami, Akira Fujita, Yasunari Fujinaga and 3 more

Open access · greenAbstract readComparative Study
In one paragraph

Article in Nagoya journal of medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. IgG4-related hypertensive granulomatous anterior uveitis.American journal of ophthalmology case reports · 2022
    Article
  5. Article
  6. Diagnostic and Staging Value of Serum Angiotensin-Converting Enzyme in Sarcoidosis.Computational and mathematical methods in medicine · 2022
    Article
  7. IgG4-related disease: a contemporary reviewTurkish journal of medical sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Yoko OzawaFirst Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Hiroshi YamamotoFirst Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Masanori YasuoFirst Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Masamichi KomatsuFirst Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Atsuhito UshikiFirst Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Hideaki HamanoSecond Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Takeshi UeharaDepartment of Laboratory Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Satoshi KawakamiDepartment of Radiology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Akira FujitaDepartment of Radiology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Yasunari FujinagaDepartment of Radiology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Kazuhiro OguchiPositron Imaging Center, Aizawa Hospital, Matsumoto, Nagano, Japan.
Shigeyuki KawaMatsumoto Dental University, Department of Internal Medicine, Shiojiri, Nagano, Japan.
Masayuki HanaokaFirst Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Shinshu University · JPAizawa Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to show the differentiation of the degree and distribution on Fluorine-18 fluorodeoxyglucose-positron emission tomography (FDG-PET) between patients with immunoglobulin G4-related disease (IgG4-RD) and sarcoidosis, though both diseases frequently show bilateral hilar lymphadenopathy (BHL). The clinical records were retrospectively reviewed in 25 patients with IgG4-RD with BHL and 15 patients with sarcoidosis (stage I-II) diagnosed at Shinshu University Hospital. All patients underwent FDG-PET at Aizawa Hospital from January 2004 to December 2015. The FDG accumulation pattern and maximum standardized uptake value (SUVmax) of the hilar lymph nodes were compared between the two groups. The IgG4-RD group (21 men; median age 69 years) showed a significant male predominance and older age compared with the sarcoidosis group (3 men, median age 55.4 years). The IgG4-RD group showed a significantly higher incidence of FDG accumulation in the lachrymal gland, submandibular gland, pancreas, prostate and periurethral and periarterial regions compared with the sarcoidosis group. In contrast, the sarcoidosis group showed a significantly higher incidence of FDG accumulation in the supraclavicular and abdominal lymph nodes, muscle and soft tissues compared with the IgG4-RD group. Furthermore, the SUVmax of the hilar lymph nodes was significantly higher in the sarcoidosis group (median 7.20) than in the IgG4-RD group (median 4.20, p=0.002). In conclusion, significant differences were observed in the FDG accumulation patterns and SUVmax values of the hilar lymph nodes between IgG4-RD with BHL and sarcoidosis, although both diseases develop through the lymphatic routes of the lungs and are frequently associated with BHL.

Indexed as

Positron-Emission TomographyAdultAgedAged, 80 and overFemaleFluorodeoxyglucose F18HumansImmunoglobulin G4-Related DiseaseLymphadenopathyLymph NodesMaleMiddle AgedPredictive Value of TestsRadiopharmaceuticalsRetrospective StudiesSarcoidosisFluorodeoxyglucose F18Radiopharmaceuticalsbilateral hilar lymphadenopathy (BHL)Fluorine-18 fluorodeoxyglucose-positron emission tomography (FDG-PET)Immunoglobulin G4-related disease (IgG4-RD)maximum standardized uptake value (SUVmax)Sarcoidosis

Identifiers

PMID32273638
PMCPMC7103870
OpenAlexW3012050099

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.