ArticleCommunications biology2020
The interrelation of sleep and mental and physical health is anchored in grey-matter neuroanatomy and under genetic control.
Article in Communications biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Obesity is associated with reduced orbitofrontal cortex volume: A coordinate-based meta-analysis.NeuroImage. Clinical · 2020Pooled it
- Longitudinal changes in cardiorespiratory fitness and risk of depressive and anxiety disorders in a nationwide cohort of 7 million participants.Scientific reports · 2026Article
- Multivariate associations of motor performance, sleep quality, depressive symptoms, and grey matter volume in younger and mid-to-older adults.Scientific reports · 2026Article
- Can we predict sleep health based on brain features? A large-scale machine learning study using the UK Biobank.Brain communications · 2026Article
- Article
- Associations between sleep, obesity, and mental health in adolescents: Understanding sex-specific vulnerabilities.Journal of affective disorders · 2025Observational
- Unraveling the connection between the Mediterranean diet and sleep health: from biological mechanisms to clinical implications.Sleep & breathing = Schlaf & Atmung · 2025Review
- Multidimensional sleep health linked to quality of life among Chinese adults.Health and quality of life outcomes · 2025Article
- Suicide risk, psychopathology and cognitive impairments in schizophrenia with insomnia: a large-scale cross-sectional study.BMC psychiatry · 2025Article
- Identification of five sleep-biopsychosocial profiles with specific neural signatures linking sleep variability with health, cognition, and lifestyle factors.PLoS biology · 2025Article
- A Systematic Review of Sleep Hygiene Strategy in CKD.Kidney international reports · 2025Article
- Evaluation of sleep-wake disorders with the Kiddie Schedule for Affective Disorders and Schizophrenia for Children and Adolescents: Present and Lifetime version 5.1.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Gut over Mind: Exploring the Powerful Gut-Brain Axis.Nutrients · 2025Review
- From surviving to thriving: How sleep, physical activity, and diet shape well-being in young adults.PloS one · 2025Article
- Space exploration and lifestyle medicine: a narrative review of its implications for astronaut health and remote Earth-based environments.Frontiers in physiology · 2025Review
- Sharing sleeping sites disrupts sleep but catalyses social tolerance and coordination between groups.Proceedings. Biological sciences · 2024Article
- Lower motor performance is linked with poor sleep quality, depressive symptoms, and grey matter volume alterations.bioRxiv : the preprint server for biology · 2024Article
- A multidimensional investigation of sleep and biopsychosocial profiles with associated neural signatures.Research square · 2024Article
- Association between electroencephalogram-based sleep characteristics and physical health in the general adult population.Scientific reports · 2023Article
- Monitoring and Predicting Health Status in Neurological Patients: The ALAMEDA Data Collection Protocol.Healthcare (Basel, Switzerland) · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
11 authors.
Funding
Abstract
Humans need about seven to nine hours of sleep per night. Sleep habits are heritable, associated with brain function and structure, and intrinsically related to well-being, mental, and physical health. However, the biological basis of the interplay of sleep and health is incompletely understood. Here we show, by combining neuroimaging and behavioral genetic approaches in two independent large-scale datasets (HCP (n = 1106), age range: 22-37, eNKI (n = 783), age range: 12-85), that sleep, mental, and physical health have a shared neurobiological basis in grey matter anatomy; and that these relationships are driven by shared genetic factors. Though local associations between sleep and cortical thickness were inconsistent across samples, we identified two robust latent components, highlighting the multivariate interdigitation of sleep, intelligence, BMI, depression, and macroscale cortical structure. Our observations provide a system-level perspective on the interrelation of sleep, mental, and physical conditions, anchored in grey-matter neuroanatomy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.