ArticleScientific reports2020
Synthesis, biological activity and molecular modeling study of novel 1,2,4-triazolo[4,3-b][1,2,4,5]tetrazines and 1,2,4-triazolo[4,3-b][1,2,4]triazines.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 44 citations in OpenAlex.
- Design, synthesis and antitubercular evaluation of novel 5,6-diphenyl-1,2,4-triazine-piperazine derivatives targeting mycobacterial dihydrofolate reductase.ADMET & DMPK · 2026Article
- Antibacterial, antibiofilm and anti-quorum sensing activities of 1,2,3,5-tetrazine derivatives linked to a benzothiazole moiety.PloS one · 2025Article
- The Volatile Organic Compounds ofMicroorganisms · 2023Article
- A novel series of pyrazole derivatives toward biological applications: experimental and conceptual DFT characterization.Molecular diversity · 2022Article
- N1/N4 1,4-Cycloaddition of 1,2,4,5-Tetrazines with Enamines Promoted by the Lewis Acid ZnClThe Journal of organic chemistry · 2022Article
- Bioprospecting endophytic fungi for bioactive metabolites and use of irradiation to improve their bioactivities.AMB Express · 2022Article
- Quinazolinone-based hybrids with diverse biological activities: A mini-review.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022Review
- Triazoles and Their Derivatives: Chemistry, Synthesis, and Therapeutic Applications.Frontiers in molecular biosciences · 2022Review
- Synthesis of novel [1,2,4]triazolo[1,5-Beilstein journal of organic chemistry · 2022Article
- Immobilization and Release Studies of Triazole Derivatives from Grafted Copolymer Based on Gellan-Carrying Betaine Units.Molecules (Basel, Switzerland) · 2021Article
- Screening and identification of abiotic stress-responsive efficient antifungalBiotechnologia · 2021Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Different novel 1,2,4-triazolo[4,3-b][1,2,4,5]tetrazines and 1,2,4-triazolo[4,3-b][1,2,4]triazines have been obtained from heterocyclization of 3-substituted-4-amino-5-substituted-amino-1,2,4-triazoles (3a-d) and 3-substituted-4-amino-5-hydrazino-1,2,4-triazoles (9a,b) with (α and β) bifunctional compounds like chloromethyl biphenyl-phosphanoxide, pyruvic acid, phenacyl bromide, diethyl oxalate, triethyl orthoformate, triethyl phosphite, fluorinated benzaldehydes, carbon disulfide and ethyl chloroformate under different experimental settings. Fourier transformer infrared analysis (FTIR), Proton nuclear magnetic resonance (
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