Evidence map›Paper›PMID 32273395›Full record

Trial reportBMJ open respiratory research2020

Reslizumab as add-on therapy in patients with refractory asthma.

J Christian Virchow, Mirna McDonald, Margaret Garin, Stephanie Korn

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMJ open respiratory research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Anti-IL-5 therapies for asthma.The Cochrane database of systematic reviews · 2022
    Pooled it
  3. Review
  4. Perspectives in Therapy of Chronic Rhinosinusitis.Diagnostics (Basel, Switzerland) · 2022
    Review
  5. Treating severe asthma: Targeting the IL-5 pathway.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2021
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

J Christian VirchowDepartments of Pneumology/Intensive Care Medicine, Universitätsmedizin, Rostock, Germany j.c.virchow@med.uni-rostock.de.ORCID http://orcid.org/0000-0003-4291-1956
Mirna McDonaldTeva Branded Pharmaceutical Products R&D Inc, West Chester, Pennsylvania, USA.
Margaret GarinTeva Branded Pharmaceutical Products R&D Inc, West Chester, Pennsylvania, USA.
Stephanie KornPulmonary Medicine, Mainz University Hospital, Mainz, Germany.
Teva Pharmaceuticals (United States) · USJohannes Gutenberg University Mainz · DEUniversitätsmedizin Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAdrenal Cortex HormonesAdrenergic beta-2 Receptor AgonistsAdultAgedAnti-Asthmatic AgentsAntibodies, Monoclonal, HumanizedAsthmaChildCost-Benefit AnalysisFemaleHumansMaleMiddle AgedPulmonary EosinophiliaRegression AnalysisAdrenal Cortex HormonesAdrenergic beta-2 Receptor AgonistsAnti-Asthmatic AgentsAntibodies, Monoclonal, Humanizedreslizumabasthmapulmonary eosinophilia

Identifiers

PMID32273395
PMCPMC7254105
OpenAlexW3015199638

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.