Evidence map›Paper›PMID 32273270›Full record

ArticleBMJ case reports2020

Increase of a wide range of bioactive substances in an active phase of neuro-Sweet disease.

Hiroi Kusaka, Katsuya Nagatani, Takeo Sato, Seiji Minota

Open access · hybridAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. New Practical Aspects of Sweet Syndrome.American journal of clinical dermatology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hiroi KusakaDivision of Rheumatology and Clinical Immunology, Jichi Medical University, Simotsuke, Tochigi, Japan.
Katsuya NagataniDivision of Rheumatology and Clinical Immunology, Jichi Medical University, Simotsuke, Tochigi, Japan knagatani@jichi.ac.jp.ORCID http://orcid.org/0000-0002-2877-189X
Takeo SatoDivision of Rheumatology and Clinical Immunology, Jichi Medical University, Simotsuke, Tochigi, Japan.
Seiji MinotaDivision of Rheumatology and Clinical Immunology, Jichi Medical University, Simotsuke, Tochigi, Japan.
Jichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a patient whose skin findings and human leucocyte antigen (HLA) typing were key findings for the diagnosis of his neuro-Sweet disease. A 55-year-old Japanese man with skin rashes and high fever suddenly developed consciousness disturbance, and brain MRI showed encephalitis and leptomeningitis. Neuro-Behçet disease or microbial infection was initially suspected, but he was eventually diagnosed with neuro-Sweet disease based on his skin rashes and pathology and the presence of HLA-B54 and Cw1. He responded to glucocorticoid and recovered without neurological sequelae. The involvement of cytokines has been implicated in the pathogenesis of Sweet disease, but the number of cytokines assayed in each case report is limited. In our patient's case, the result of a 27-cytokine assay showed increases in a wide range of bioactive substances including inflammatory cytokines, growth factors and chemoattractants in the active phase, indicating the involvement of multiple cytokines in the pathogenesis of Sweet disease.

Indexed as

CytokinesDiagnosis, DifferentialEncephalitisGlucocorticoidsHumansMaleMeningitisMiddle AgedPrednisoloneSweet SyndromeCytokinesGlucocorticoidsPrednisoloneconnective tissue diseasevasculitis

Identifiers

PMID32273270
PMCPMC7244277
OpenAlexW3015276448

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.