ReviewPatient education and counseling2020
Patients' understanding of oncology clinical endpoints: A literature review.
Review in Patient education and counseling, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Patient Understanding of Oncology Clinical Trial Endpoints in Direct-to-Consumer Television Advertising.The oncologist · 2023Trial
- From Prototype to Practice: Mixed Methods Study of Human-Centered Design and Usability Evaluation of Augmented Reality for Complex Oncology Surgical Workflows.JMIR human factors · 2026Article
- Sexual Silence in Breast Cancer Survivorship: A Secondary Qualitative Study of Healthcare Practices and Sexual Concerns.Health science reports · 2026Article
- FDA Accelerated Approval Disclosures on Direct-to-Consumer Prescription Drug Websites: Testing Presence, Prominence, and Wording.Therapeutic innovation & regulatory science · 2026Article
- Cancer Survivors' and Caregivers' Understanding of FDA Accelerated Approval Disclosures.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025Article
- Outcomes that matter to patients with cancer: living longer and living better.EClinicalMedicine · 2024Review
- Patient Enrollment per Month (Accrual) in Clinical Trials Leading to the FDA Approval of New Cancer Drugs.Targeted oncology · 2024Article
- Healthcare providers' understanding of data displays of clinical trial information: a scoping review of the literature.Journal of communication in healthcare · 2023Article
- Article
- Communication of anticancer drug benefits and related uncertainties to patients and clinicians: document analysis of regulated information on prescription drugs in Europe.BMJ (Clinical research ed.) · 2023Article
- Knowledge and attitudes towards clinical trials among women with ovarian cancer: results of the ACTO study.Journal of ovarian research · 2022Observational
- Selection of endpoints in breast cancer clinical trials: a qualitative study of key trial stakeholders.American journal of cancer research · 2022Article
- News coverage of drug development: implications for the conveyance of health information.BMC public health · 2021Article
- Patients' Understanding of Oncology Clinical Endpoints: Environmental Scan and Focus Groups.The oncologist · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
objectivesOncology clinical trials use a variety of clinical endpoints. Patients' understanding of the differences between clinical endpoints is important because misperceptions of treatment efficacy may affect treatment decisions. The objective of this literature review is to find and synthesize available empirical publications assessing patients' understanding of common oncology clinical endpoints.
methodsWe conducted a literature search of 5 databases and 3 conferences, limiting the search to articles and abstracts published in English through September 2018. We reviewed the titles and abstracts for inclusion, then reviewed full texts to determine if they reported empirical research studies focused on (1) clinical endpoints, (2) oncology, and (3) patient understanding. The original search identified 497publications, of which 13 met the inclusion criteria.
resultsAvailable literature yields little information on this topic.The few publications that do exist suggest that healthcare professionals and cancer patients generally do not discuss clinical endpoint concepts and that patients can be confused about the purpose of a treatment based on misperceptions about endpoints.
conclusionsResearch is needed on how to discuss oncology clinical endpoints with patients. PRACTICE IMPLICATIONS: Patient-friendly definitions of clinical endpoints may help healthcare providers communicate important information about treatments to patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.