ArticleJournal of clinical medicine2020
Left Ventricle Unloading with Veno-Arterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock. Systematic Review and Meta-Analysis.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Early left ventricular unloading during extracorporeal membrane oxygenation in cardiogenic shock: A systematic review and meta-analysis.Artificial organs · 2025Pooled it
- Predictors of Mortality in Patients Treated with Veno-Arterial ECMO for Cardiogenic Shock Complicating Acute Myocardial Infarction: a Systematic Review and Meta-Analysis.Journal of cardiovascular translational research · 2022Pooled it
- Temporary Mechanical Circulatory Support in Patients in Cardiogenic Shock Requiring Cardiac Surgery: Protected Cardiac Surgery Concept.Journal of clinical medicine · 2026Review
- Transaortic Catheter Venting for Left Ventricular Unloading in Veno-Arterial Extracorporeal Life Support: A Porcine Cardiogenic Shock Model.Medicina (Kaunas, Lithuania) · 2025Article
- Efficacy of ultrasound guided venous cannulation positioning during venous-arterial extracorporeal membrane oxygenation.Frontiers in cardiovascular medicine · 2025Article
- Differential effect of left ventricular unloading according to the aetiology of cardiogenic shock.ESC heart failure · 2024Observational
- Extracorporeal Membrane Oxygenation (VA-ECMO) in Management of Cardiogenic Shock.Journal of clinical medicine · 2023Review
- Review
- Emerging concepts in heart failure management and treatment: circulatory support with extracorporeal membrane oxygenation (ECMO).Drugs in context · 2023Review
- Interactions between extracorporeal support and the cardiopulmonary system.Frontiers in physiology · 2023Review
- Improving Survival in Cardiogenic Shock-A Propensity Score-Matched Analysis of the Impact of an Institutional Allocation Protocol to Short-Term Mechanical Circulatory Support.Life (Basel, Switzerland) · 2022Article
- Extracorporeal membrane oxygenation and left ventricular unloading: What is the evidence?JTCVS techniques · 2022Article
- Echocardiography for extracorporeal membrane oxygenation.Echocardiography (Mount Kisco, N.Y.) · 2022Review
- Controversies in extracorporeal membrane oxygenation: Immediate versus watchful waiting for venoarterial extracorporeal membrane oxygenation venting.JTCVS open · 2021Article
- Article
- Article
- Hemodynamic variations and pitfalls during venoarterial extracorporeal membrane oxygenation and left ventricular apical unloading as bridge to heart transplantation.Journal of cardiology cases · 2021Article
- Management of cardiogenic shock.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2021Review
- The Surgeon's Role in Cardiogenic Shock.Current heart failure reports · 2021Review
- Venoarterial Extracorporeal Membrane Oxygenation for Postcardiotomy Shock-Analysis of the Extracorporeal Life Support Organization Registry.Critical care medicine · 2021Article
Corrections and comments
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Authors and funding
11 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During veno-arterial extracorporeal membrane oxygenation (VA-ECMO), the increase of left ventricular (LV) afterload can potentially increase the LV stress, exacerbate myocardial ischemia and delay recovery from cardiogenic shock (CS). Several strategies of LV unloading have been proposed. Systematic review and meta-analysis in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement included adult patients from studies published between January 2000 and March 2019. The search was conducted through numerous databases. Overall, from 62 papers, 7581 patients were included, among whom 3337 (44.0%) received LV unloading concomitant to VA-ECMO. Overall, in-hospital mortality was 58.9% (4466/7581). A concomitant strategy of LV unloading as compared to ECMO alone was associated with 12% lower mortality risk (RR 0.88; 95% CI 0.82-0.93;
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.